Vandenplas Yvan, Hauser Bruno
a Department of Pediatrics, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium.
Expert Rev Gastroenterol Hepatol. 2015;9(12):1511-21. doi: 10.1586/17474124.2015.1093932. Epub 2015 Sep 28.
Comprehensive guidelines for the diagnosis and management of gastro-esophageal reflux (GER) and GER disease (GERD) were developed by the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition. GERD is reflux associated with troublesome symptoms or complications. The recognition of GER and GERD is relevant to implement best management practices. A conservative management is indicated in infants with uncomplicated physiologic reflux. Children with GERD may benefit from further evaluation and treatment. Since the publications of the European and North American Societies for Pediatric Gastroenterology, Hepatology and Nutrition guidelines in 2009, no important novelties in drug treatment have been reported. Innovations are mainly restricted to the management of regurgitation in infants. During the last 5 years, pros and cons of multichannel intraluminal impedance have been highlighted. However, overall 'not much has changed' in the diagnosis and management of GER and GERD in infants and children.
欧洲和北美小儿胃肠病、肝病和营养学会制定了胃食管反流（GER）和胃食管反流病（GERD）诊断与管理的综合指南。GERD是与令人烦恼的症状或并发症相关的反流。认识GER和GERD对于实施最佳管理实践至关重要。对于无并发症的生理性反流婴儿，建议采用保守管理。GERD患儿可能会从进一步评估和治疗中受益。自2009年欧洲和北美小儿胃肠病、肝病和营养学会发布指南以来，尚未有关于药物治疗方面重要新进展的报道。创新主要局限于婴儿反流的管理。在过去5年中，多通道腔内阻抗的利弊已得到凸显。然而，婴幼儿GER和GERD的诊断与管理总体上“变化不大”。
