Leake Devin
IEEE Pulse. 2015 Sep-Oct;6(5):26-8. doi: 10.1109/MPUL.2015.2456248.
As scientists make strides toward the goal of developing a form of biological engineering that's as predictive and reliable as chemical engineering is for chemistry, one technology component has become absolutely critical: gene synthesis. Gene synthesis is the process of building stretches of deoxyribonucleic acid (DNA) to order--some stretches based on DNA that exists already in nature, some based on novel designs intended to accomplish new functions. This process is the foundation of synthetic biology, which is rapidly becoming the engineering counterpart to biology.
随着科学家们朝着开发一种像化学工程对化学那样具有预测性和可靠性的生物工程形式的目标大步迈进,一种技术组件已变得绝对至关重要:基因合成。基因合成是按顺序构建脱氧核糖核酸(DNA)片段的过程——一些片段基于自然界中已存在的DNA,一些基于旨在实现新功能的新颖设计。这个过程是合成生物学的基础,而合成生物学正迅速成为生物学的工程对应物。