水中氟西汀对斑马鱼应激反应和渗透调节的影响。
Effects of waterborne fluoxetine on stress response and osmoregulation in zebrafish.
作者信息
Abreu Murilo S, Giacomini Ana Cristina V, Koakoski Gessi, Oliveira Thiago A, Gusso Darlan, Baldisserotto Bernardo, Barcellos Leonardo J G
机构信息
Universidade Federal de Santa Maria (UFSM), Programa de Pós-Graduação em Farmacologia, Campus Universitário, Camobi, Santa Maria, RS, Brazil.
Universidade Federal de Santa Maria (UFSM), Programa de Pós-Graduação em Farmacologia, Campus Universitário, Camobi, Santa Maria, RS, Brazil; Universidade de Passo Fundo (UPF), Programa de Pós-Graduação em Bioexperimentação, Campus I, Bairro São José, Caixa Postal 611, Passo Fundo, RS, Brazil.
出版信息
Environ Toxicol Pharmacol. 2015 Nov;40(3):704-7. doi: 10.1016/j.etap.2015.09.001. Epub 2015 Sep 8.
The presence of fluoxetine in aquatic environments has been reported for decades. Here, we investigate the effects of exposure to fluoxetine on the stress response and osmoregulation in zebrafish. We show that stress response alters osmoregulation and that fluoxetine inhibits these stress-related changes in osmoregulation. The results suggest that the presence of fluoxetine in aquatic ecosystems can cause changes in response to stress and osmoregulation in fish.
几十年来，人们一直报道水生环境中存在氟西汀。在此，我们研究了暴露于氟西汀对斑马鱼应激反应和渗透调节的影响。我们发现应激反应会改变渗透调节，而氟西汀会抑制这些与应激相关的渗透调节变化。结果表明，水生生态系统中氟西汀的存在会导致鱼类对应激和渗透调节的反应发生变化。
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