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体外干细胞向生殖细胞的分化。

In vitro Differentiation of Germ Cells from Stem Cells.

机构信息

Bio-X Institutes, Shanghai Jiao Tong University, No. 800. Dongchuan Road, Minhang District, Shanghai, 200240, China.

出版信息

Curr Mol Pharmacol. 2016;9(4):305-310. doi: 10.2174/1874467208666150928154053.

Abstract

Stem cells are unique cell types with the ability of self-renewal and differentiation, which mainly include embryonic stem cells, induced pluripotent stem cells, and adult stem cells. Recently, several research groups have reported that stem cells can differentiate into germ cells under appropriate conditions in vitro. Advances in this field have revealed new perspectives for reproductive and regenerative medicine. Here, we review the progress of in vitro gamete production from stem cells.

摘要

干细胞是具有自我更新和分化能力的独特细胞类型,主要包括胚胎干细胞、诱导多能干细胞和成人干细胞。最近,有几个研究小组报告说,在适当的条件下,干细胞可以在体外分化为生殖细胞。该领域的进展为生殖和再生医学带来了新的视角。在这里,我们回顾了从干细胞体外产生配子的进展。

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