Xicohténcatl-Rugerio Irving, Corona-Quintanilla Dora Luz, Nicolás Leticia, Martínez-Gómez Margarita, Cuevas Estela, Castelán Francisco, Rodríguez-Antolín Jorge
Doctorado en Neuroetología, Universidad Veracruzana, Xalapa, Veracruz, México.
Centro Tlaxcala de Biología de la Conducta, Universidad Autónoma de Tlaxcala, Tlaxcala, México.
Neurourol Urodyn. 2017 Jan;36(1):80-85. doi: 10.1002/nau.22891. Epub 2015 Sep 28.
To determine the response of the pubococcygeus muscle (Pcm) during the urethrogenital reflex (UGR).
Urethane-anesthetized male rats (n = 20) were used to describe the gross anatomy of the Pcm (n = 3), the effect of the electrical stimulation of the Pcm on the urethral pressure (n = 3), and the reflex activity of the Pcm due to the mechanical stimulation of the urethra (n = 3) and during penile and urethrogenital reflexes (n = 11). The urethral pressure (UP) was recorded as a response to penile stimulation (brushing, extension, and occlusion) and during the UGR; the electromyographic activity of the Pcm was simultaneously evaluated. The role of the Pcm was assessed by measuring urethral pressure variables before and after denervation of this muscle.
The Pcm is innervated by the caudal branch of the somatomotor branch of the pelvic nerve. The electrically induced contraction of the Pcm increased the UP. The mechanical stimulation of the urethra during the induced micturition caused the reflex activity of the Pcm. The different penile stimuli caused bursts of activity of the Pcm. During the UGR, the Pcm exhibited a tonic activity. The transection of the caudal branch of the Smb reduced the maximal UP during the penile stimulation. The same was true regarding the duration of the UGR, the pressure that triggers the UGR, and the highest pressure observed during the UGR.
Our results suggest that the activation of the Pcm is relevant for the UGR in male rats. Neurourol. Urodynam. 36:80-85, 2017. © 2015 Wiley Periodicals, Inc.
确定耻骨尾骨肌（Pcm）在尿道生殖反射（UGR）过程中的反应。
使用氨基甲酸乙酯麻醉的雄性大鼠（n = 20）来描述Pcm的大体解剖结构（n = 3）、Pcm电刺激对尿道压力的影响（n = 3）以及尿道机械刺激（n = 3）和阴茎及尿道生殖反射期间（n = 11）Pcm的反射活动。记录尿道压力（UP）作为对阴茎刺激（刷洗、伸展和闭塞）以及UGR期间的反应；同时评估Pcm的肌电图活动。通过测量该肌肉去神经前后的尿道压力变量来评估Pcm的作用。
Pcm由盆神经躯体运动支的尾部分支支配。Pcm的电诱导收缩增加了UP。诱导排尿期间尿道的机械刺激引起Pcm的反射活动。不同的阴茎刺激引起Pcm的活动爆发。在UGR期间，Pcm表现出紧张性活动。Smb尾部分支的横断减少了阴茎刺激期间的最大UP。UGR的持续时间、触发UGR的压力以及UGR期间观察到的最高压力情况也是如此。
我们的结果表明，Pcm的激活与雄性大鼠的UGR相关。《神经泌尿学与尿动力学》36:80 - 85，2017年。© 2015威利期刊公司
