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焦虑症中皮肤电反应习惯化率的临床意义

Clinical significance of the electrodermal habituation rate in anxiety disorders.

作者信息

Rabavilas A D

机构信息

Athens University Medical School Department of Psychiatry, Eginition Hospital Greece.

出版信息

Neuropsychobiology. 1989;22(2):68-71. doi: 10.1159/000118594.

DOI:10.1159/000118594
PMID:2641794
Abstract

The electrodermal response habituation rate (EDR-HR) is examined in relation to clinical, personality and electrodermal measures in patients with generalized anxiety, phobic, obsessive-compulsive, dysthymic and conversion disorders by means of a stepwise regression analysis procedure. The results in the entire sample suggest that EDR-HR depends on the phasic component (amplitude and spontaneous activity) of the electrodermal response as well as on state anxiety, extraversion and depersonalization. When tested separately, most of the diagnostic groups demonstrated main trends similar to those found in total patients. A noteworthy correspondence between the importance of the contribution of certain clinical symptoms to the EDR-HR variance and some long-standing views of psychopathology was also found during the separate analysis of the groups. Although these findings question the diagnostic specificity of EDR-HR, the importance of this index as an objective measure of change following a therapeutic intervention as well as its potential usefulness in high-risk studies of anxiety disorders is put forward.

摘要

通过逐步回归分析程序,研究广泛性焦虑症、恐惧症、强迫症、心境恶劣障碍和转换障碍患者的皮肤电反应习惯化率(EDR-HR)与临床、人格及皮肤电测量指标之间的关系。整个样本的结果表明,EDR-HR取决于皮肤电反应的时相成分(幅度和自发活动)以及状态焦虑、外向性和人格解体。单独测试时,大多数诊断组显示出与全部患者相似的主要趋势。在各诊断组的单独分析中,还发现某些临床症状对EDR-HR方差贡献的重要性与一些长期存在的精神病理学观点之间存在显著对应关系。尽管这些发现对EDR-HR的诊断特异性提出了质疑,但该指标作为治疗干预后变化的客观测量指标的重要性及其在焦虑症高危研究中的潜在用途也被提了出来。

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