基于聚集诱导发光的滚环扩增实时监测：在生物检测中的应用
Real-time monitoring of rolling circle amplification using aggregation-induced emission: applications in biological detection.
作者信息
Jiang Hong-Xin, Zhao Meng-Yao, Niu Chen-Di, Kong De-Ming
机构信息
State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, People's Republic of China.
出版信息
Chem Commun (Camb). 2015 Nov 28;51(92):16518-21. doi: 10.1039/c5cc07340e.
PMID:26417952
Abstract
We report that QATPE, an aggregation-induced emission-active tetraphenylethene dye, can be used as a non-sequence-specific ssDNA probe for real-time monitoring of all rolling circle amplification (RCA) reactions, thus making RCA more suitable for biosensing applications.
摘要
我们报道，四苯乙烯染料QATPE具有聚集诱导发光活性，可作为一种非序列特异性的单链DNA探针，用于实时监测所有滚环扩增（RCA）反应，从而使RCA更适用于生物传感应用。
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