Lillie Edwardina Mary Mae Alexandra, Holmes Christopher John, O'Donohoe Elizabeth Anne, Bowen Lowri, Ngwisha Chadwick L T, Ahmed Yusuf, Snell David Michael, Kinnear John Alexander, Bould M Dylan
Department of Anaesthesia, Guys and St Thomas' Hospital, London, UK.
Department of Anaesthesia, Great Ormond Street Hospital, London, UK.
Can J Anaesth. 2015 Dec;62(12):1259-67. doi: 10.1007/s12630-015-0483-z. Epub 2015 Sep 29.
Perioperative mortality has fallen in both high- and low-income countries over the last 50 years. An evaluation of avoidable perioperative mortality can provide valuable lessons to improve care; however, there is relatively little recent data from the Least Developed Countries in the world. We aimed to compare recent avoidable perioperative mortality in Lusaka, Zambia, with historical data from 1987.
We conducted a retrospective cohort study by identifying perioperative deaths within days of surgery and comparing the operating room and mortuary registers for the 2012 calendar year. Multiple independent raters from anesthesiology and surgery/obstetrics gynecology reviewed case notes, when available, to identify avoidable causes of death.
Of the 18,010 surgical patients in 2012, 114 were identified as having died perioperatively within six days of surgery. Fifty-nine files were available for further analysis (52% of identified perioperative deaths). Eighteen (30%) of these cases were assessed as avoidable, 19 cases (32%) probably avoidable, 14 cases (24%) unavoidable, and eight cases (14%) unclear. Thirty-one (53%) cases had surgical factors contributing to death, 19 (32%) cases had anesthesia factors, and 18 (30%) cases had systems factors. Most of the avoidable deaths were attributed to multiple factors. Key factors leading to the avoidable deaths were delays in surgery, lack of the availability of blood, and poor postoperative care.
Most deaths were avoidable, suggesting that patient outcomes in low-resource settings can be improved within current resources. The multifactorial nature of avoidability implies that an interprofessional approach is required to improve the quality of care.
在过去50年里,高收入国家和低收入国家的围手术期死亡率均有所下降。对可避免的围手术期死亡率进行评估可为改善医疗护理提供宝贵经验;然而,世界上最不发达国家近期的数据相对较少。我们旨在将赞比亚卢萨卡近期可避免的围手术期死亡率与1987年的历史数据进行比较。
我们通过确定手术后数天内的围手术期死亡病例,并比较2012年日历年的手术室和太平间登记册,开展了一项回顾性队列研究。来自麻醉科以及外科/妇产科的多名独立评估人员在有病例记录时对其进行审查,以确定可避免的死亡原因。
2012年的18010例外科手术患者中,有114例被确定在手术后6天内围手术期死亡。59份档案可供进一步分析(占已确定围手术期死亡病例的52%)。其中18例(30%)被评估为可避免死亡,19例(32%)可能可避免,14例(24%)不可避免,8例(14%)情况不明。31例(53%)病例有导致死亡的手术因素,19例(32%)病例有麻醉因素,18例(30%)病例有系统因素。大多数可避免死亡归因于多种因素。导致可避免死亡的关键因素是手术延误、血液供应不足和术后护理不佳。
大多数死亡是可避免的,这表明在资源有限的情况下,利用现有资源可以改善患者的治疗结果。可避免性的多因素性质意味着需要采取跨专业方法来提高护理质量。