Khan Mueenullah, Khan Fauzia A
Dept. of Anaesthesia, Aga Khan Univ. Karachi, Pakistan.
Middle East J Anaesthesiol. 2007 Feb;19(1):159-72.
It is important to ascertain the contribution of anesthesia to perioperative mortality in order to enable improvement in the safety and quality of care. Scanty literature regarding anesthetic mortality from developing countries is available. We present data regarding anesthesia related mortality in a university hospital in a developing country. We reviewed all patient deaths occurring between 1992-2003 occurring within 24 hours of anesthesia, as part of departmental quality assurance activity. The aim of study was to identify any contributing factors associated with mortality, and to compare our data with similar studies from developed and developing countries. 111,289 cases were handled in this period. Within 24 hours the crude mortality was 35 (3.14: 10,000). 3 patients died at induction, 13 intraoperatively and one at emergence. In the postoperative period 18 (51%) cases of mortality occurred. In 4 (11%) cases anesthesia was found to be solely responsible (0.35 per 10,000), in 8 (23%) cases anesthesia was found to be partially responsible (0.7 per 10,000). In 23 patient disease and surgical factors played a primary role. In 10 (28.5%) cases deaths were considered to be avoidable. Two time periods were also compared. Between 1992-1998 anesthesia mortality was 0.68: 10,000 anesthetics, and from 1999-2003 it was 0.18: 10,000 Higher mortality was observed with advancing age, higher ASA status, emergency and complex surgical procedures. Human factor, human error, inadequate preoperative preparation, inappropriate postoperative care and lack of supervision were identified as preventable factors.
为了提高围手术期护理的安全性和质量,确定麻醉对围手术期死亡率的影响至关重要。目前关于发展中国家麻醉死亡率的文献较少。我们提供了一个发展中国家一家大学医院麻醉相关死亡率的数据。作为部门质量保证活动的一部分,我们回顾了1992年至2003年间在麻醉后24小时内发生的所有患者死亡情况。本研究的目的是确定与死亡率相关的任何影响因素,并将我们的数据与来自发达国家和发展中国家的类似研究进行比较。在此期间共处理了111,289例病例。24小时内的粗死亡率为35例(3.14:10,000)。3例患者在诱导期死亡,13例在手术中死亡,1例在苏醒期死亡。术后有18例(51%)发生死亡。在4例(11%)病例中,发现麻醉是唯一死因(每10,000例中有0.35例),在8例(23%)病例中,发现麻醉部分有责(每10,000例中有0.7例)。在23例患者中,疾病和手术因素起主要作用。在10例(28.5%)病例中,死亡被认为是可以避免的。还比较了两个时间段。1992年至1998年期间麻醉死亡率为每10,000例麻醉中有0.68例,1999年至2003年期间为每10,000例中有0.18例。随着年龄增长、ASA分级升高、急诊和复杂手术,死亡率更高。人为因素、人为失误、术前准备不足、术后护理不当和缺乏监督被确定为可预防因素。