Miyamoto Wataru, Takao Masato, Miki Shinya, Kawano Hirotaka
Teikyo University School of Medicine, Tokyo, Japan.
Int Orthop. 2016 May;40(5):959-64. doi: 10.1007/s00264-015-3005-2. Epub 2015 Sep 29.
We aimed to evaluate the midterm clinical results of osteochondral autograft transplantation (OAT) for advanced stage Freiberg disease.
This study included consecutive patients who underwent OAT for advanced stage Freiberg disease and were followed postoperatively for more than five years. In all cases, the autograft was harvested from the ipsilateral knee joint. Clinical evaluation was performed based on the American Orthopaedic Foot and Ankle Society Lesser Metatarsophalangeal-Interphalangeal Scale (AOFAS) score and visual analogue scale (VAS) score, which were done pre-operatively and at the most recent follow-up. Radiological evaluation was performed at two years after the operation. Furthermore, the most recent six patients underwent magnetic resonance imaging (MRI) five years after the operation to assess the configuration of the articular surface.
A total of 13 patients (all female; mean age 16.7 years; range 10-38 years) were included and followed up for a mean duration of 67.2 months (range 60-100 months). The mean AOFAS significantly improved from a score of 66.9 ± 5.3 (range 59-77) to 93.0 ± 7.6 (range 82-100) (p < 0.0001). Likewise, the mean VAS significantly improved from a score of 72.7 ± 10.3 (range 60-90) to 7.8 ± 7.2 (range 0-20) (p < 0.0001). Radiographs at two years after the operation revealed no osteoarthritic change in all cases. MRI at five years after the operation showed consolidation of the transplanted autograft and smooth configuration of the articular surface in the six cases.
OAT may be effective for advanced stage Freiberg disease. Further studies are necessary before this technique can become the standard operative treatment.
我们旨在评估自体骨软骨移植(OAT)治疗晚期弗赖伯格病的中期临床效果。
本研究纳入了因晚期弗赖伯格病接受OAT并术后随访超过五年的连续患者。所有病例中,自体移植物均取自同侧膝关节。基于美国矫形足踝协会小跖趾关节-趾间关节量表(AOFAS)评分和视觉模拟量表(VAS)评分进行临床评估,评估在术前和最近一次随访时进行。术后两年进行影像学评估。此外,最近的6例患者在术后五年接受了磁共振成像(MRI)检查,以评估关节面的形态。
共纳入13例患者(均为女性;平均年龄16.7岁;范围10 - 38岁),平均随访时间为67.2个月(范围60 - 100个月)。AOFAS平均评分从66.9±5.3(范围59 - 77)显著提高至93.0±7.6(范围82 - 100)(p < 0.0001)。同样,VAS平均评分从72.7±10.3(范围60 - 90)显著提高至7.8±7.2(范围0 - 20)(p < 0.0001)。术后两年的X线片显示所有病例均无骨关节炎改变。术后五年的MRI显示6例患者移植的自体移植物愈合,关节面形态光滑。
OAT可能对晚期弗赖伯格病有效。在该技术成为标准手术治疗方法之前,还需要进一步研究。