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猫原发性肺肿瘤:计算机断层扫描结果评估与生存情况

Primary pulmonary neoplasia in cats: assessment of computed tomography findings and survival.

作者信息

Nunley J, Sutton J, Culp W, Wilson D, Coleman K, Demianiuk R, Schechter A, Moore G, Donovan T, Schwartz P

机构信息

Animal Medical Center, New York, NY 10065, USA.

University of California-Davis, Davis, CA 95616, USA.

出版信息

J Small Anim Pract. 2015 Nov;56(11):651-6. doi: 10.1111/jsap.12401. Epub 2015 Sep 30.

DOI:10.1111/jsap.12401
PMID:26420583
Abstract

OBJECTIVE

To identify variables with a preoperative computed tomography scan that influence survival of cats undergoing surgical removal of a primary lung tumour. A secondary objective was to determine whether histologic type and or grade of feline pulmonary tumours affects long term survival.

METHODS

Medical records were retrospectively reviewed for cats with preoperative computed tomography scans and surgical resection of primary lung tumours. Pulmonary carcinomas were reviewed for histologic diagnosis using two different approaches, histologic grade as well as major histologic pattern.

RESULTS

Median survival time of all (n = 28) cats was 156 days. Median survival time for cats with lymph node enlargement was 65 days versus 498 days for cats without lymph node enlargement on preoperative computed tomography scan. Median survival time for cats with preoperative pleural effusion was 2 · 5 days versus 467 days for cats without pleural effusion. Cats with low or intermediate grade tumours had a median survival time of 730 days versus 105 days for cats with high grade tumours.

CLINICAL SIGNIFICANCE

Cats with preoperative lymph node enlargement and pleural effusion have shorter survival times than cats without.

摘要

目的

确定术前计算机断层扫描中影响原发性肺肿瘤手术切除猫生存的变量。次要目的是确定猫肺肿瘤的组织学类型和/或分级是否影响长期生存。

方法

对有术前计算机断层扫描和原发性肺肿瘤手术切除的猫的病历进行回顾性审查。使用两种不同方法对肺癌进行组织学诊断,包括组织学分级以及主要组织学模式。

结果

所有(n = 28)猫的中位生存时间为156天。术前计算机断层扫描显示有淋巴结肿大的猫的中位生存时间为65天,而无淋巴结肿大的猫为498天。术前有胸腔积液的猫的中位生存时间为2.5天,而无胸腔积液的猫为467天。低级别或中级别的肿瘤猫的中位生存时间为730天,而高级别肿瘤猫为105天。

临床意义

术前有淋巴结肿大和胸腔积液的猫的生存时间比没有这些情况的猫短。

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