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在不进行髌骨表面置换的全膝关节置换术中,髌骨去神经支配有必要吗?

Is patellar denervation necessary in total knee arthroplasty without patellar resurfacing?

作者信息

Zhang Peng, Liu Hao, Yan Wen-Shan, Wang Wen-Liang

机构信息

Department of Orthopedic Center, Affiliated Hospital of Logistics University of the Chinese People's Armed Police Forces, Tianjin, China.

Department of Orthopedic, The Chinese People's Armed Police Forces in Fujian Province, Longyan, China.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2016 Aug;24(8):2541-9. doi: 10.1007/s00167-015-3811-5. Epub 2015 Sep 30.

Abstract

PURPOSE

To conduct a meta-analysis with randomized controlled trials (RCTs) published in full text to determine the effectiveness of patellar denervation (PD) in primary total knee arthroplasty (TKA).

METHODS

Literature search was performed in PubMed, Embase, Web of Science and Cochrane Library for information from the earliest date of data collection to February 2015. RCTs comparing the benefits and risks of PD with those of no patellar denervation (NPD) in primary TKAs were included. Statistical heterogeneity was quantitatively evaluated by X(2) test with the significance set P < 0.10 or I (2) > 50 %.

RESULTS

Six RCTs consisting of 751 patients were included. The incidences of AKP in PD group and NPD group were 38.3 % (90/235) and 46.3 % (107/231), respectively. Meta-analysis showed significant prevention effect of PD on the incidence of AKP (OR 0.65; 95 % CI 0.42, 1.00; P = 0.05) without significant heterogeneity (I (2) = 44 %, P = 0.15). Our results also indicated that PD was significantly associated with better American Knee Society knee (WMD = 2.50; 95 % CI 0.34, 4.67; P = 0.02) and functional scores (WMD = 4.07; 95 % CI 1.34, 6.80; P = 0.0003) and range of motion (ROM) (WMD = 4.27; 95 % CI 1.95, 6.60; P = 0.0003) compared with NPD. However, there was no significant difference between the two groups no matter in Oxford knee score, patellar score or visual analogue scale at any other time. Complications and revisions did not differ significantly between the two groups.

CONCLUSION

This meta-analysis showed that PD in TKAs without patellar resurfacing, compared with NPD, could prevent the incidence of post-operative AKP and improve clinical outcome in KSS and post-operative ROM. Based on the above results, PD was a safe procedure with no significant complications and revision or re-operations.

LEVEL OF EVIDENCE

Therapeutic study, Level II.

摘要

目的

通过对全文发表的随机对照试验(RCT)进行荟萃分析,以确定髌骨去神经支配术(PD)在初次全膝关节置换术(TKA)中的有效性。

方法

在PubMed、Embase、科学网和Cochrane图书馆进行文献检索,以获取从数据收集最早日期至2015年2月的信息。纳入比较PD与非髌骨去神经支配术(NPD)在初次TKA中的益处和风险的RCT。通过X²检验对统计异质性进行定量评估,显著性设定为P < 0.10或I² > 50%。

结果

纳入了6项RCT,共751例患者。PD组和NPD组的碱性磷酸酶(AKP)发生率分别为38.3%(90/235)和46.3%(107/231)。荟萃分析显示,PD对AKP发生率有显著预防作用(比值比[OR] 0.65;95%置信区间[CI] 0.42,1.00;P = 0.05),且无显著异质性(I² = 44%,P = 0.15)。我们的结果还表明,与NPD相比,PD与更好的美国膝关节协会膝关节评分(加权均数差[WMD] = 2.50;95% CI 0.34,4.67;P = 0.02)、功能评分(WMD = 4.07;95% CI 1.34,6.80;P = 0.0003)以及活动范围(ROM)(WMD = 4.27;95% CI 1.95,6.60;P = 0.0003)显著相关。然而,在任何其他时间,两组在牛津膝关节评分、髌骨评分或视觉模拟量表方面均无显著差异。两组之间的并发症和翻修情况无显著差异。

结论

这项荟萃分析表明,在未进行髌骨表面置换的TKA中,与NPD相比,PD可预防术后AKP的发生率,并改善膝关节协会评分(KSS)和术后ROM的临床结局。基于上述结果,PD是一种安全的手术,无显著并发症,无需翻修或再次手术。

证据水平

治疗性研究,二级。

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