Xie XiaoWei, Pei FuXing, Huang ZeYu, Tan Zhen, Yang Zhouyuan, Kang PengDe
Department of Orthopaedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu, 610041, People's Republic of China,
Knee Surg Sports Traumatol Arthrosc. 2015 Jun;23(6):1808-15. doi: 10.1007/s00167-015-3566-z. Epub 2015 Mar 11.
The effectiveness of patellar denervation in reducing anterior knee pain and improving patient satisfaction and quality of life after total knee arthroplasty (TKA) is still controversial. A meta-analysis was conducted to try to settle the controversy.
The electronic databases PubMed, Web of Science, Embase, and Cochrane Library were systematically searched. Of 374 papers identified, seven randomised controlled trials involving 898 patients (983 knees) were eligible for data extraction and meta-analysis.
Analysis showed that patellar denervation can significantly improve clinical outcomes for the first 12 months of follow-up after TKA, including anterior knee pain incidence (P = 0.008), visual analogue scale score (P < 0.001), patellar score (P < 0.001), Knee Society Score (P = 0.03), Knee Society Score function score (P = 0.03), and knee range of motion (P = 0.008). However, no statistical significance in outcomes was found between the patellar denervation group and no-denervation group for any of those parameters after 12 months of follow-up.
The best currently available evidence suggests that patellar denervation can significantly reduce anterior knee pain incidence and improve early clinical outcomes after TKA. However, after a prolonged period of follow-up, this advantage seems to disappear. Even so, the use of patellar denervation in primary TKA is recommended because it is safe and produces good early clinical outcomes.
Therapeutic study, Level II.
髌骨去神经支配术在全膝关节置换术(TKA)后减轻膝关节前部疼痛、提高患者满意度和生活质量方面的有效性仍存在争议。进行一项荟萃分析以试图解决这一争议。
系统检索电子数据库PubMed、科学网、Embase和Cochrane图书馆。在检索到的374篇论文中,7项涉及898例患者(983膝)的随机对照试验符合数据提取和荟萃分析的条件。
分析表明,髌骨去神经支配术可显著改善TKA后随访的前12个月的临床结果,包括膝关节前部疼痛发生率(P = 0.008)、视觉模拟评分(P < 0.001)、髌骨评分(P < 0.001)、膝关节协会评分(P = 0.03)、膝关节协会评分功能评分(P = 0.03)和膝关节活动范围(P = 0.008)。然而,随访12个月后,髌骨去神经支配组与未去神经支配组在任何这些参数的结果上均未发现统计学差异。
目前可得的最佳证据表明,髌骨去神经支配术可显著降低TKA后膝关节前部疼痛发生率并改善早期临床结果。然而,经过长时间随访,这一优势似乎消失。即便如此,仍建议在初次TKA中使用髌骨去神经支配术,因为它安全且能产生良好的早期临床结果。
治疗性研究,二级。