Kattapuram S V, Phillips W C, Mankin H J
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
Radiology. 1989 Jan;170(1 Pt 1):137-41. doi: 10.1148/radiology.170.1.2642339.
The authors retrospectively evaluated the clinical records and radiographs of 20 patients with a variety of neoplasms in the long bones treated with local resection and allograft replacement. All of the tumors were peridiaphyseal and required an interposed (intercalary) segmental allograft replacement. Postoperative complications developed in 40% of the patients. However, the eventual clinical outcome was good or excellent in 85% of all cases. Various factors appeared to be responsible for the development of complications or the eventual clinical outcome, including union of the graft with the host tissue, soft-tissue swelling, callus formation, and type of allograft (hemi or full). Knowledge of these factors and the relationship between complications and radiographic findings may lead to an early diagnosis and appropriate treatment.
作者回顾性评估了20例长骨患有各种肿瘤并接受局部切除和同种异体骨移植替代治疗的患者的临床记录和X线片。所有肿瘤均位于骨干周围,需要植入(节段性)同种异体骨进行替代。40%的患者出现了术后并发症。然而,在所有病例中,最终临床结果为良好或优秀的占85%。各种因素似乎与并发症的发生或最终临床结果有关,包括移植物与宿主组织的愈合、软组织肿胀、骨痂形成以及同种异体骨的类型(半关节或全关节)。了解这些因素以及并发症与影像学表现之间的关系可能有助于早期诊断和恰当治疗。