Yuh W T, Hunsicker L G, Nghiem D D, Sato Y, Smith J L, Wright F H, Corry R J
Department of Radiology, University of Iowa Hospital and Clinic, Iowa City 55242.
Radiology. 1989 Jan;170(1 Pt 1):171-7. doi: 10.1148/radiology.170.1.2642341.
Eighty-eight magnetic resonance (MR) imaging studies of 31 pancreas transplants in 30 patients were performed. The postoperative graft usually appears enlarged and inhomogeneous, with patchy areas of increased signal intensity on T2-weighted images that may last 3-4 weeks. During acute rejection, T1-weighted images of graft abnormalities show a decrease in signal intensity, similar to that of muscle, and T2-weighted images show an increase in signal intensity, equal to or higher than that of the bladder. The pattern of abnormal signal is most frequently multifocal but can be diffuse, and the graft may be enlarged. During recovery from rejection, the graft parenchyma shows a decrease in signal intensity (less than that of the bladder) on T2-weighted images when compared with that of acute rejection. During chronic rejection the graft is small and shows low signal intensity, slightly higher than or similar to that of muscle, on both T1- and T2-weighted images. MR imaging appears to be useful for detection of early pancreas allograft rejection and complications in conjunction with clinical findings, laboratory data, and other radiologic procedures.
对30例患者的31次胰腺移植进行了88次磁共振（MR）成像研究。术后移植物通常会肿大且不均匀，在T2加权图像上有片状信号强度增加区域，这种情况可能持续3 - 4周。在急性排斥反应期间，移植物异常的T1加权图像显示信号强度降低，与肌肉相似，而T2加权图像显示信号强度增加，等于或高于膀胱。异常信号模式最常见为多灶性，但也可为弥漫性，移植物可能会肿大。在排斥反应恢复期间，与急性排斥反应相比，移植物实质在T2加权图像上显示信号强度降低（低于膀胱）。在慢性排斥反应期间，移植物较小，在T1加权和T2加权图像上均显示低信号强度，略高于或类似于肌肉。结合临床发现、实验室数据和其他放射学检查，MR成像似乎有助于检测早期胰腺同种异体移植排斥反应和并发症。
