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使用氰基丙烯酸正丁酯进行咯血支气管动脉栓塞术的三轴系统

Triaxial system in bronchial arterial embolization for haemoptysis using N-butyl-2-cyanoacrylate.

作者信息

Shimohira Masashi, Hashimoto Takeshi, Abematsu Saori, Hashizume Takuya, Nakagawa Motoo, Ozawa Yoshiyuki, Sakurai Keita, Shibamoto Yuta

机构信息

1 Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

2 Department of Radiology, Kouseikai Hospital, Toyohashi, Japan.

出版信息

Br J Radiol. 2015;88(1056):20150265. doi: 10.1259/bjr.20150265. Epub 2015 Oct 1.

DOI:10.1259/bjr.20150265
PMID:26423598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4984931/
Abstract

OBJECTIVE

The application of bronchial artery embolization (BAE) using N-butyl-2-cyanoacrylate (NBCA) for haemoptysis was recently reported to be useful. A triple co-axial (triaxial) system consisting of a 4-Fr catheter, 2.7-Fr microcatheter and 1.9-Fr no-taper microcatheter has been developed. The aim of the present study was to evaluate the usefulness of the triaxial system in BAE using NBCA.

METHODS

12 patients with haemoptysis, 8 males and 4 females with a median age of 64 years (range, 49-88 years), underwent BAE between August 2012 and October 2014. Medical records and images were reviewed, and the technical success rate, clinical success rate, haemoptysis-free rate and complications were evaluated. Technical success was defined as the complete cessation of the target artery as confirmed by digital subtraction angiography, whereas clinical success was defined as the cessation of haemoptysis within 24 h of BAE. Recurrent haemoptysis was defined as a total of >30 ml of bleeding per day.

RESULTS

The target artery was embolized successfully in all patients, and the technical success rate was 100% (12/12). The cessation of haemoptysis was achieved in 11 out of 12 patients within 24 h, and thus, the clinical success rate was 92% (11/12). The 6-, 12- and 24-month haemoptysis-free rates were 89%, 89% and 76%, respectively. No patients exhibited any signs of complications such as spinal ischaemia.

CONCLUSION

BAE using the triaxial system and NBCA appears to be a useful and safe procedure for haemoptysis.

ADVANCES IN KNOWLEDGE

The triaxial system contributes to safe and effective BAE using NBCA.

摘要

目的

最近有报道称,使用N-丁基-2-氰基丙烯酸酯(NBCA)进行支气管动脉栓塞术(BAE)治疗咯血是有效的。一种由4F导管、2.7F微导管和1.9F无锥度微导管组成的三同轴系统已被研发出来。本研究的目的是评估该三同轴系统在使用NBCA进行BAE中的有效性。

方法

2012年8月至2014年10月期间,12例咯血患者接受了BAE,其中男性8例,女性4例,中位年龄64岁(范围49 - 88岁)。回顾了病历和影像资料,并评估了技术成功率、临床成功率、无咯血率和并发症情况。技术成功定义为经数字减影血管造影证实目标动脉完全闭塞,而临床成功定义为BAE后24小时内咯血停止。复发性咯血定义为每天出血总量>30ml。

结果

所有患者的目标动脉均成功栓塞,技术成功率为100%(12/12)。12例患者中有11例在24小时内咯血停止,因此临床成功率为92%(11/12)。6个月、12个月和24个月的无咯血率分别为89%、89%和76%。没有患者出现任何并发症迹象,如脊髓缺血。

结论

使用三同轴系统和NBCA进行BAE似乎是一种治疗咯血有用且安全的方法。

知识进展

三同轴系统有助于使用NBCA安全有效地进行BAE。

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