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Androgen deprivation therapy for prostate cancer: friend or foe to the cardiovascular system?

作者信息

Zhang Kaiping, Zhang Li, Hao Zongyao, Liang Chaozhao

机构信息

Department of Urology, The First Affiliated Hospital of Anhui Medical University, and Institute of Urology, Anhui Medical University, No. 218 Jixi Road, Hefei, 230022, Anhui Province, People's Republic of China.

出版信息

World J Urol. 2016 Jun;34(6):879-81. doi: 10.1007/s00345-015-1700-7. Epub 2015 Sep 30.

DOI:10.1007/s00345-015-1700-7
PMID:26424563
Abstract
摘要

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Androgen deprivation therapy for prostate cancer: friend or foe to the cardiovascular system?前列腺癌的雄激素剥夺治疗:对心血管系统是福是祸?
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Does the benefit justify the risk?益处是否大于风险?
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J Natl Cancer Inst. 2010 Jan 6;102(1):39-46. doi: 10.1093/jnci/djp404. Epub 2009 Dec 7.
4
Weighing up the risks and benefits of androgen deprivation therapy.权衡雄激素剥夺疗法的风险与益处。
Practitioner. 2014 May;258(1771):5.
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Metabolic syndrome and prostate cancer: a review.代谢综合征与前列腺癌:综述
Clin Oncol (R Coll Radiol). 2009 Apr;21(3):183-91. doi: 10.1016/j.clon.2008.11.013. Epub 2008 Dec 25.
6
Is hormone ablation still the right choice for advanced prostate cancer?激素消融疗法对晚期前列腺癌来说仍是正确的选择吗?
BJU Int. 2007 Jul;100 Suppl 2:36-9. doi: 10.1111/j.1464-410X.2007.06952.x.
7
Prevalence of Cardiovascular Disease and Osteoporosis During Androgen Deprivation Therapy Prescription Discordant to EAU Guidelines: Results From a Multicenter, Cross-sectional Analysis From the CHOsIng Treatment for Prostate canCEr (CHOICE) Study.与欧洲泌尿外科学会(EAU)指南不符的雄激素剥夺治疗处方期间心血管疾病和骨质疏松症的患病率:前列腺癌选择治疗(CHOICE)研究的多中心横断面分析结果
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Androgen-deprivation therapy and cardiovascular harm: let's not throw out the baby with the bathwater.雄激素剥夺疗法与心血管损害:我们不要因噎废食。
Eur Urol. 2014 Apr;65(4):710-2. doi: 10.1016/j.eururo.2013.03.002. Epub 2013 Mar 13.
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Re: Christina G. Jespersen, Mette Nørgaard, Michael Borre. Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study.回复:克里斯蒂娜·G·耶斯佩森、梅特·诺尔加德、迈克尔·博勒。雄激素剥夺疗法治疗前列腺癌与心肌梗死和中风风险:一项基于丹麦全国人群的队列研究。
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Safety and Therapeutic Profile of a GnRH-Based Vaccine Candidate Directed to Prostate Cancer. A 10-Year Follow-Up of Patients Vaccinated With Heberprovac.一种针对前列腺癌的基于促性腺激素释放激素(GnRH)的候选疫苗的安全性和治疗概况。对接种赫伯普罗瓦克疫苗的患者进行的10年随访。
Front Oncol. 2019 Feb 25;9:49. doi: 10.3389/fonc.2019.00049. eCollection 2019.

本文引用的文献

1
Preventing aggressive prostate cancer with proven cardiovascular disease preventive methods.用已证实的心血管疾病预防方法预防侵袭性前列腺癌。
Asian J Androl. 2015 Nov-Dec;17(6):874-7; discussion 876. doi: 10.4103/1008-682X.156854.
2
Cancer statistics, 2015.癌症统计数据,2015 年。
CA Cancer J Clin. 2015 Jan-Feb;65(1):5-29. doi: 10.3322/caac.21254. Epub 2015 Jan 5.
3
Androgen deprivation therapy in castrate-resistant prostate cancer: how important is GnRH agonist backbone therapy?去势抵抗性前列腺癌中的雄激素剥夺治疗:促性腺激素释放激素激动剂基础治疗有多重要?
World J Urol. 2015 Aug;33(8):1079-85. doi: 10.1007/s00345-014-1406-2. Epub 2014 Sep 27.
4
Improving intermittent androgen deprivation therapy: lessons learned from basic and translational research.改善间歇性雄激素剥夺疗法:基础研究与转化研究的经验教训
Asian J Androl. 2014 Jul-Aug;16(4):505-10. doi: 10.4103/1008-682X.125410.
5
The impact of androgen-deprivation therapy (ADT) on the risk of cardiovascular (CV) events in patients with non-metastatic prostate cancer: a population-based study.雄激素剥夺疗法(ADT)对非转移性前列腺癌患者心血管(CV)事件风险的影响:一项基于人群的研究。
BJU Int. 2014 Dec;114(6b):E82-E89. doi: 10.1111/bju.12732. Epub 2014 Jul 27.
6
Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study.雄激素剥夺疗法治疗前列腺癌与心肌梗死和中风风险:一项基于全国丹麦人群的队列研究。
Eur Urol. 2014 Apr;65(4):704-9. doi: 10.1016/j.eururo.2013.02.002. Epub 2013 Feb 12.
7
Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer.雄激素剥夺治疗期间的糖尿病与心血管疾病:前列腺癌退伍军人的观察性研究
J Natl Cancer Inst. 2012 Oct 3;104(19):1518-23. doi: 10.1093/jnci/djs376.
8
Patients with prostate cancer treated by ADT have significantly higher fibrinogenemia than healthy control.接受 ADT 治疗的前列腺癌患者的纤维蛋白原血症显著高于健康对照组。
World J Urol. 2013 Apr;31(2):289-92. doi: 10.1007/s00345-012-0926-x. Epub 2012 Aug 17.
9
Absolute and relative risk of cardiovascular disease in men with prostate cancer: results from the Population-Based PCBaSe Sweden.男性前列腺癌患者的心血管疾病绝对风险和相对风险:基于人群的瑞典 PCBaSe 研究结果。
J Clin Oncol. 2010 Jul 20;28(21):3448-56. doi: 10.1200/JCO.2010.29.1567. Epub 2010 Jun 21.
10
Impact of androgen deprivation therapy on cardiovascular disease and diabetes.雄激素剥夺疗法对心血管疾病和糖尿病的影响。
J Clin Oncol. 2009 Jul 20;27(21):3452-8. doi: 10.1200/JCO.2008.20.0923. Epub 2009 Jun 8.