来自德国的五株人畜共患猪链球菌菌株的特性分析，包括一株从近期一名猎人致命性链球菌中毒性休克样综合征病例中分离出的菌株。
Characterization of Five Zoonotic Streptococcus suis Strains from Germany, Including One Isolate from a Recent Fatal Case of Streptococcal Toxic Shock-Like Syndrome in a Hunter.
作者信息
Eisenberg Tobias, Hudemann Christoph, Hossain Hamid M, Hewer Angela, Tello Khodr, Bandorski Dirk, Rohde Manfred, Valentin-Weigand Peter, Baums Christoph Georg
机构信息
Hessian State Laboratory, Department of Veterinary Medicine, Giessen, Germany.
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps University Marburg, Marburg, Germany.
出版信息
J Clin Microbiol. 2015 Dec;53(12):3912-5. doi: 10.1128/JCM.02578-15. Epub 2015 Sep 30.
Abstract
A Streptococcus suis isolate from a German hunter with streptococcal toxic shock-like syndrome (STSLS) and four additional zoonotic isolates were genotyped as mrp(+) epf* (variant 1890) sly(+) cps2(+). All five zoonotic German strains were characterized by high multiplication in human blood samples ex vivo, but induction of only low levels of proinflammatory cytokines compared to a Chinese STSLS strain.
摘要
从一名患有链球菌中毒性休克样综合征（STSLS）的德国猎人身上分离出的一株猪链球菌，以及另外四株人畜共患病原体分离株，被基因分型为mrp(+) epf*(变体1890) sly(+) cps2(+)。与一株中国STSLS菌株相比，所有五株德国人畜共患病原体菌株的特征是在体外人血样本中具有高增殖能力，但仅诱导产生低水平的促炎细胞因子。
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