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CT增强扫描显示的单发小病灶,特别是针对神经囊尾蚴病:我的治疗方法。

Single small enhancing CT Lesions, with special reference to neurocysticercosis: How I treat.

作者信息

Padma Srivastava M V

机构信息

Professor, Head Unit III Neurology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Ann Indian Acad Neurol. 2015 Jul-Sep;18(3):286-9. doi: 10.4103/0972-2327.162269.

DOI:10.4103/0972-2327.162269
PMID:26425004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4564461/
Abstract

Single small enhancing CT lesions (SSECTL) have been very commonly encountered in clinical practice. These lesions typically are small (often < 20 mm), enhancing as a ring lesion or a disc and with varying amounts of surrounding edema. Most SSECTL present as focal seizures. Once the diagnosis of SSECTL and likely to be a solitary cysticercus lesion is made, the patient is given appropriate AED therapy. Depending on the resolution pattern on repeat imaging performed at intervals not less than six months if patient remains asymptomatic, cysticidal therapy is instituted along with AEDs. Any deviation from the classical clinical or radiological patterns needs further evaluation and other etiologies described for the SSECTL will need to be ruled out, including that of tuberculosis. Largely these lesions resolve and the clinical condition remains benign and in most patients AEDs can be withdrawn in two to three years period.

摘要

单个小的增强CT病变(SSECTL)在临床实践中非常常见。这些病变通常较小(常<20mm),表现为环形或盘状增强,周围有不同程度的水肿。大多数SSECTL表现为局灶性癫痫发作。一旦诊断为SSECTL且可能为孤立性囊尾蚴病变,就给予患者适当的抗癫痫药物(AED)治疗。如果患者无症状,根据间隔不少于6个月进行的重复成像的消退模式,在给予AED的同时开始杀虫治疗。任何偏离经典临床或放射学模式的情况都需要进一步评估,需要排除SSECTL的其他病因,包括结核病。这些病变大多会消退,临床状况保持良性,大多数患者在两到三年内可以停用AED。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/456d/4564461/3aea55c830b4/AIAN-18-286-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/456d/4564461/3aea55c830b4/AIAN-18-286-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/456d/4564461/3aea55c830b4/AIAN-18-286-g002.jpg

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本文引用的文献

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Anthelmintics for people with neurocysticercosis.用于治疗神经囊尾蚴病患者的驱虫药。
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Combination therapy with albendazole and praziquantel versus albendazole alone in children with seizures and single lesion neurocysticercosis: a randomized, placebo-controlled double blind trial.阿苯达唑与吡喹酮联合治疗与阿苯达唑单药治疗儿童癫痫发作和单病灶神经囊尾蚴病的对比:一项随机、安慰剂对照双盲试验。
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Single small enhancing CT lesions in Indian patients with epilepsy: clinical, radiological and pathological considerations.印度癫痫患者中CT显示的单个小强化病灶:临床、放射学及病理学考量
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