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甲状腺手术中喉返神经的电生理神经监测:当前文献综述

Electrophysiological neural monitoring of the laryngeal nerves in thyroid surgery: review of the current literature.

作者信息

Deniwar Ahmed, Kandil Emad, Randolph Gregory

机构信息

1 Department of Surgery, School of Medicine, Tulane University, New Orleans, USA ; 2 Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, USA.

出版信息

Gland Surg. 2015 Oct;4(5):368-75. doi: 10.3978/j.issn.2227-684X.2015.04.04.

DOI:10.3978/j.issn.2227-684X.2015.04.04
PMID:26425449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4561657/
Abstract

Recurrent laryngeal nerve (RLN) injury is one of the most common complications of thyroid surgery. RLN injury can cause vocal cord paralysis, affecting the patient's voice and the quality of life. Injury of the external branch of the superior laryngeal nerve (EBSLN) can cause cricothyroid muscle denervation affecting high vocal tones. Thus, securing the laryngeal nerves in these surgeries is of utmost importance. Visual identification of the nerves has long been the standard method for this precaution. Intraoperative neuromonitoring (IONM) has been introduced as a novel technology to improve the protection of the laryngeal nerves and reduce the rate of RLN injury. The aim of this article is to provide a brief description of the technique and review the literature to illustrate the value of IONM. IONM can provide early identification of anatomical variations and unusual nerve routes, which carry a higher risk of injury if not detected. IONM helps in prognosticating postoperative nerve function. Moreover, by detecting nerve injury intraoperatively, it aids in staging bilateral surgeries to avoid bilateral vocal cord paralysis and tracheostomy. The article will discuss the value of continuous IONM (C-IOMN) that may prevent nerve injury by detecting EMG waveform changes indicating impending nerve injury. Herein, we are also discussing anatomy of laryngeal nerves and aspects of its injury.

摘要

喉返神经(RLN)损伤是甲状腺手术最常见的并发症之一。喉返神经损伤可导致声带麻痹,影响患者的嗓音和生活质量。喉上神经外支(EBSLN)损伤可导致环甲肌失神经支配,影响高音调。因此,在这些手术中保护喉神经至关重要。长期以来,直视下识别神经一直是这种预防措施的标准方法。术中神经监测(IONM)作为一种新技术被引入,以改善喉神经的保护并降低喉返神经损伤率。本文旨在简要描述该技术并回顾文献以阐明术中神经监测的价值。术中神经监测可早期识别解剖变异和异常神经走行,如果未被发现,这些情况会带来更高的损伤风险。术中神经监测有助于预测术后神经功能。此外,通过术中检测神经损伤,它有助于安排双侧手术分期,以避免双侧声带麻痹和气管切开术。本文将讨论连续术中神经监测(C-IOMN)的价值,其可通过检测表明即将发生神经损伤的肌电图波形变化来预防神经损伤。在此,我们还将讨论喉神经的解剖结构及其损伤的相关方面。

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本文引用的文献

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Electrophysiologic identification and monitoring of the external branch of superior laryngeal nerve during thyroidectomy.甲状腺切除术中喉上神经外支的电生理识别与监测
Laryngoscope. 2015 Aug;125(8):1996-2000. doi: 10.1002/lary.25139. Epub 2015 Jan 13.
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Does intraoperative nerve monitoring reliably aid in staging of total thyroidectomies?术中神经监测能否可靠地辅助全甲状腺切除术的分期?
Laryngoscope. 2015 Sep;125(9):2232-5. doi: 10.1002/lary.25133. Epub 2015 Jan 19.
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Gender, race, and electrophysiologic characteristics of the branched recurrent laryngeal nerve.喉返神经分支的性别、种族及电生理特征
Laryngoscope. 2014 Oct;124(10):2433-7. doi: 10.1002/lary.24631. Epub 2014 Mar 25.
4
Correlation of final evoked potential amplitudes on intraoperative electromyography of the recurrent laryngeal nerve with immediate postoperative vocal fold function after thyroid and parathyroid surgery.喉返神经术中肌电图的终末诱发电位幅度与甲状腺和甲状旁腺手术后即刻声带功能的相关性。
JAMA Otolaryngol Head Neck Surg. 2014 Feb;140(2):124-8. doi: 10.1001/jamaoto.2013.6139.
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Continuous monitoring of the recurrent laryngeal nerve in thyroid surgery: a critical appraisal.甲状腺手术中喉返神经的连续监测:批判性评价。
Int J Surg. 2013;11 Suppl 1:S44-6. doi: 10.1016/S1743-9191(13)60014-X.
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Continuous vagal IONM prevents recurrent laryngeal nerve paralysis by revealing initial EMG changes of impending neuropraxic injury: a prospective, multicenter study.连续监测迷走神经可通过揭示即将发生的神经失用性损伤的初始肌电图变化来预防喉返神经麻痹:一项前瞻性、多中心研究。
Laryngoscope. 2014 Jun;124(6):1498-505. doi: 10.1002/lary.24550. Epub 2014 Feb 6.
7
The impact of surgical volume on patient outcomes following thyroid surgery.手术量对甲状腺手术后患者结局的影响。
Surgery. 2013 Dec;154(6):1346-52; discussion 1352-3. doi: 10.1016/j.surg.2013.04.068.
8
Electrophysiologic monitoring characteristics of the recurrent laryngeal nerve preoperatively paralyzed or invaded with malignancy.术前因恶性肿瘤而瘫痪或受侵犯的喉返神经的电生理监测特征。
Otolaryngol Head Neck Surg. 2013 Nov;149(5):682-8. doi: 10.1177/0194599813504735. Epub 2013 Sep 17.
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Intraoperative recurrent laryngeal nerve monitoring in thyroid surgery: is it really useful?甲状腺手术中喉返神经的术中监测:它真的有用吗?
Clin Ter. 2013 May-Jun;164(3):e193-8. doi: 10.7417/CT.2013.1567.
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External branch of the superior laryngeal nerve monitoring during thyroid and parathyroid surgery: International Neural Monitoring Study Group standards guideline statement.喉上神经外支监测在甲状腺和甲状旁腺手术中的应用:国际神经监测研究组标准指南声明。
Laryngoscope. 2013 Sep;123 Suppl 4:S1-14. doi: 10.1002/lary.24301.