Vinutha H T, Raghavendra B R, Manjunath N K
Department of Psychophysiology, Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana (a Deemed University), Bengaluru, India.
Indian J Endocrinol Metab. 2015 Sep-Oct;19(5):653-7. doi: 10.4103/2230-8210.163194.
Integrated approach of yoga therapy (IAYT) had shown beneficial effects in the management of type 2 diabetes mellitus (DM). Autonomic dysfunction is one of the major complications of type 2 DM. Research studies have demonstrated that yoga can modulate autonomic functions. Hence, the current study was designed to assess the effect of IAYT on autonomic functions in type 2 diabetics.
15 patients of type 2 DM with ages ranging from 35 to 60 years were recruited for the study. They were diagnosed with type 2 diabetes from 1-year to 15 years. Assessments were made on day 1 (before yoga) and day 7 (after 1-week of yoga practice). Heart rate variability (HRV), blood pressure (BP) response to the isometric handgrip and heart rate response to deep breathing were assessed before and after 1-week of IAYT.
There was a significant reduction in fasting plasma glucose from 154.67-130.27 mg/dL (Wilcoxon signed rank test, P = 0.029) following 1-week of IAYT. BP response to isometric hand grip improved significantly (Wilcoxon signed rank test, P = 0.01). There was no statistical significant change in HRV components and heart rate response to deep breathing test. However, there was a trend of increase in the low frequency power (41.07%), high frequency power (6.29%), total power (5.38%), and standard deviation of all NN intervals (SDNN) (6.29%).
These findings suggest that, IAYT improved autonomic functions in type 2 diabetes patients.
瑜伽疗法综合方案（IAYT）已显示出在2型糖尿病（DM）管理中的有益效果。自主神经功能障碍是2型糖尿病的主要并发症之一。研究表明瑜伽可调节自主神经功能。因此，本研究旨在评估IAYT对2型糖尿病患者自主神经功能的影响。
招募了15名年龄在35至60岁之间的2型糖尿病患者进行研究。他们被诊断为2型糖尿病1至15年。在第1天（瑜伽前）和第7天（瑜伽练习1周后）进行评估。在IAYT 1周前后评估心率变异性（HRV）、等长握力时的血压（BP）反应以及深呼吸时的心率反应。
IAYT 1周后，空腹血糖从154.67降至130.27mg/dL，差异有统计学意义（Wilcoxon符号秩检验，P = 0.029）。等长握力时的BP反应显著改善（Wilcoxon符号秩检验，P = 0.01）。HRV各成分及深呼吸试验时的心率反应无统计学显著变化。然而，低频功率（41.07%）、高频功率（6.29%）、总功率（5.38%）和所有NN间期标准差（SDNN）（6.29%）有增加趋势。
这些发现表明，IAYT改善了2型糖尿病患者的自主神经功能。
