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基于瑜伽疗法的综合瑜伽模块在改善高血压患者心血管功能和血脂水平中的作用:一项随机对照试验。

The Role of Integrated Approach to Yoga Therapy-Based Yoga Module in Improving Cardiovascular Functions and Lipid Profile in Hypertensive Patients: A Randomized Controlled Trial.

作者信息

Shetty Shivaprasad, Nandeesh N S, Shetty Prashanth

机构信息

Department of Yoga Therapeutics, SDMCNYS, Ujire, Karnataka, India.

Department of Yoga and Naturopathy, SDMCNYS, Ujire, Karnataka, India.

出版信息

Int J Yoga. 2022 Sep-Dec;15(3):215-221. doi: 10.4103/ijoy.ijoy_107_22. Epub 2023 Jan 16.

Abstract

BACKGROUND

Hypertension is a growing public health problem and its optimal management is imperative. Integration of lifestyle modification and yoga with antihypertensive drugs leads to its successful management. Yoga has been shown to modulate blood pressure (BP) and lipid metabolism in individuals with hypertension. The current study is a preliminary effort to ascertain the underlying mechanisms behind it.

MATERIALS AND METHODS

Hundred patients were screened, among which 65 who met the inclusion criteria were recruited. After baseline assessments, they were randomly allocated (1:1) to an intervention group (IG) who practiced integrated approach to yoga therapy (IAYT)-based yoga module for 6 days a week, for 3 months and a control group (CG) who received no intervention. BP, heart rate variability, and lipid profile were assessed before and after the intervention. Data acquired from 60 cases were analyzed by analysis for multiple comparisons between the mean values.

RESULTS

At the end of 3 months, within-group comparison showed significant changes ( < 0.05) in IG in all variables except triglycerides, high-density lipoprotein (HDL), and very low-density lipoprotein (LDL) while similar changes were not present in the control group. Significant differences were seen between the groups in the TC ( = 0.005), HDL ( = 0.047), non-HDL ( = 0.013), LDL ( < 0.001), LDL/HDL Ratio ( = 0.031), CHOL/HDL Ratio ( = 0.043), DBP ( < 0.001), SBP ( < 0.001), and all indices of HRV ( < 0.001).

CONCLUSION

These findings suggest that IAYT-based yoga module was effective in improving cardiovascular performance and lipid metabolism, thereby mitigating coronary artery disease risk.

摘要

背景

高血压是一个日益严重的公共卫生问题,对其进行优化管理势在必行。将生活方式改变和瑜伽与降压药物相结合可成功管理高血压。研究表明,瑜伽可调节高血压患者的血压(BP)和脂质代谢。本研究是确定其潜在机制的初步尝试。

材料与方法

筛查了100名患者,其中65名符合纳入标准的患者被招募。在进行基线评估后,他们被随机分配(1:1)到干预组(IG),该组每周进行6天基于综合瑜伽疗法(IAYT)的瑜伽模块练习,持续3个月;以及对照组(CG),该组不接受任何干预。在干预前后评估血压、心率变异性和血脂谱。对从60例病例中获取的数据进行均值之间的多重比较分析。

结果

在3个月末,组内比较显示,干预组除甘油三酯、高密度脂蛋白(HDL)和极低密度脂蛋白(LDL)外,所有变量均有显著变化(<0.05),而对照组未出现类似变化。两组在总胆固醇(TC,=0.005)、HDL(=0.047)、非HDL(=0.013)、LDL(<0.001)、LDL/HDL比值(=0.031)、CHOL/HDL比值(=0.043)、舒张压(DBP,<0.001)、收缩压(SBP,<0.001)以及所有心率变异性指标(<0.001)方面存在显著差异。

结论

这些发现表明,基于IAYT的瑜伽模块可有效改善心血管功能和脂质代谢,从而降低冠状动脉疾病风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c99/10026340/b340316d33b2/IJY-15-215-g001.jpg

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