Dietrich Martin F, Cavuoti Dominick, Landay Michael, Arriaga Yull E
University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Investig Med High Impact Case Rep. 2014 Nov 23;2(4):2324709614560216. doi: 10.1177/2324709614560216. eCollection 2014 Oct-Dec.
Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.
肺转移是骨巨细胞瘤罕见的并发症。我们在此描述了一例有趣的病例,源于骨原发性巨细胞瘤的肺转移灶在接受RANK配体抑制剂地诺单抗治疗后出现组织学消退和体积缩小。