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RANK配体抑制后骨巨细胞瘤的组织学消退

Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition.

作者信息

Dietrich Martin F, Cavuoti Dominick, Landay Michael, Arriaga Yull E

机构信息

University of Texas Southwestern Medical Center, Dallas, TX, USA.

出版信息

J Investig Med High Impact Case Rep. 2014 Nov 23;2(4):2324709614560216. doi: 10.1177/2324709614560216. eCollection 2014 Oct-Dec.

Abstract

Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.

摘要

肺转移是骨巨细胞瘤罕见的并发症。我们在此描述了一例有趣的病例,源于骨原发性巨细胞瘤的肺转移灶在接受RANK配体抑制剂地诺单抗治疗后出现组织学消退和体积缩小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2221/4528877/643061167ee3/10.1177_2324709614560216-fig1.jpg

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