Rotzinger Roman, Bläker Hendrik, Bahra Marcus, Denecke Timm, Grieser Christian
Charité-Universitätsmedizin Berlin, Berlin, Germany.
J Investig Med High Impact Case Rep. 2015 Mar 16;3(1):2324709615576988. doi: 10.1177/2324709615576988. eCollection 2015 Jan-Mar.
Autoimmune pancreatitis is a rare type of chronic pancreatitis. It is supposed to be a pancreatic manifestation of an immune-complex modulated systemic disorder. In contrast, pancreatic adenocarcinoma is the most frequent malignant neoplasm of the pancreas. Within the rare type of focal autoimmune pancreatitis, only few presentations with multifocal pancreatic lesions have been described. Herein we report a case of a 58-year-old patient with autoimmune pancreatitis presenting with bifocal manifestations of the pancreatic head and tail, mimicking pancreatic adenocarcinoma clinically, on computed tomography and magnetic resonance imaging. Typical imaging findings of autoimmune pancreatitis are compared with typical findings in pancreatic carcinoma. The diagnostic dilemma of differentiating between both entities is discussed. A review of the present literature regarding multifocal presence of autoimmune pancreatitis is performed.
自身免疫性胰腺炎是一种罕见的慢性胰腺炎类型。它被认为是一种免疫复合物介导的全身性疾病的胰腺表现。相比之下,胰腺腺癌是胰腺最常见的恶性肿瘤。在罕见的局灶性自身免疫性胰腺炎类型中,仅有少数多灶性胰腺病变的病例报道。在此,我们报告一例58岁自身免疫性胰腺炎患者,其胰头和胰尾出现双灶性表现,在计算机断层扫描和磁共振成像上临床上酷似胰腺腺癌。将自身免疫性胰腺炎的典型影像学表现与胰腺癌的典型表现进行了比较。讨论了鉴别这两种疾病的诊断难题。并对目前关于自身免疫性胰腺炎多灶性存在的文献进行了综述。