How Much HIV is Alive? The Challenge of Measuring Replication Competent HIV for HIV Cure Research.
作者信息
Ananworanich Jintanat, Mellors John W
机构信息
U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA ; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
The University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
EBioMedicine. 2015 Jul 29;2(8):788-9. doi: 10.1016/j.ebiom.2015.07.036. eCollection 2015 Aug.
Abstract
摘要
相似文献
1
How Much HIV is Alive? The Challenge of Measuring Replication Competent HIV for HIV Cure Research.有多少HIV是存活的？为艾滋病治愈研究测量具有复制能力的HIV所面临的挑战。
EBioMedicine. 2015 Jul 29;2(8):788-9. doi: 10.1016/j.ebiom.2015.07.036. eCollection 2015 Aug.
2
No cure yet for HIV-1, but therapeutic research presses on.目前仍没有治愈HIV-1的方法，但治疗研究仍在继续。
J Infect Dis. 2007 Mar 15;195(6):770-2. doi: 10.1086/511830. Epub 2007 Jan 30.
3
Is cure possible for HIV?艾滋病病毒有可能被治愈吗？
AIDS Treat News. 2007 Jan-Jun(422):6-7.
4
Gene therapy for HIV-1 infection: are lethal genes a valuable tool?针对HIV-1感染的基因治疗：致死基因是一种有价值的工具吗？
Cell Mol Biol (Noisy-le-grand). 2005 Sep 2;51(1):93-101.
5
Cell therapies for treatment of human immunodeficiency virus infection.细胞疗法治疗人类免疫缺陷病毒感染。
Rev Med Virol. 2015 May;25(3):156-74. doi: 10.1002/rmv.1831. Epub 2015 Mar 2.
6
Is a pacific coexistence between virus and host the unexploited path that may lead to an HIV functional cure?病毒和宿主之间的和平共处是否是一条未被开发的途径，可能导致 HIV 功能性治愈？
Viruses. 2013 Feb 21;5(2):753-7. doi: 10.3390/v5020753.
7
Molecular mechanisms for the regulation of HIV replication, persistence and latency.调节HIV复制、持续性和潜伏性的分子机制。
AIDS. 1997;11 Suppl A:S25-33.
8
T cell-based functional cDNA library screening identified SEC14-like 1a carboxy-terminal domain as a negative regulator of human immunodeficiency virus replication.基于 T 细胞的功能性 cDNA 文库筛选鉴定 SEC14 样蛋白 1a 羧基末端结构域是人类免疫缺陷病毒复制的负调控因子。
Vaccine. 2010 May 26;28 Suppl 2:B68-74. doi: 10.1016/j.vaccine.2009.07.084.
9
[HIV infection].
Rev Prat. 2012 Feb;62(2):255-62.
10
Inhibition of HIV replication by the plasminogen activator is dependent on vitronectin-mediated cell adhesion.纤溶酶原激活剂对HIV复制的抑制作用依赖于玻连蛋白介导的细胞黏附。
J Leukoc Biol. 2007 Nov;82(5):1212-20. doi: 10.1189/jlb.0407251. Epub 2007 Aug 17.
引用本文的文献
1
Inducible HIV-1 Reservoir Quantification: Clinical Relevance, Applications and Advancements of TILDA.可诱导的HIV-1储存库定量：TILDA的临床相关性、应用及进展
Front Microbiol. 2021 Jun 15;12:686690. doi: 10.3389/fmicb.2021.686690. eCollection 2021.
2
TZA, a Sensitive Reporter Cell-based Assay to Accurately and Rapidly Quantify Inducible, Replication-competent Latent HIV-1 from Resting CD4 T Cells.TZA，一种基于敏感报告细胞的检测方法，用于准确快速地定量来自静息CD4 T细胞的可诱导、具有复制能力的潜伏性HIV-1。
Bio Protoc. 2019 May 20;9(10). doi: 10.21769/BioProtoc.3232.
3
Establishment of latent HIV-1 reservoirs: what do we really know?潜伏性HIV-1储存库的建立：我们究竟了解多少？
J Virus Erad. 2019 Jan 1;5(1):3-9. doi: 10.1016/S2055-6640(20)30275-2.
4
TZA: a novel assay for measuring the latent HIV-1 reservoir.TZA：一种用于测量潜伏性HIV-1储存库的新型检测方法。
Expert Rev Mol Diagn. 2017 Dec;17(12):1033-1035. doi: 10.1080/14737159.2017.1384315. Epub 2017 Sep 28.
5
Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4 T cells.新型检测方法揭示了静息CD4 T细胞中存在一个庞大的、可诱导的、具有复制能力的HIV-1病毒库。
Nat Med. 2017 Jul;23(7):885-889. doi: 10.1038/nm.4347. Epub 2017 May 29.
6
Are T cells the only HIV-1 reservoir?T细胞是唯一的HIV-1储存库吗？
Retrovirology. 2016 Dec 20;13(1):86. doi: 10.1186/s12977-016-0323-4.
本文引用的文献
1
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.一种用于测量 HIV 感染者中诱导性病毒储存库大小的新方法。
EBioMedicine. 2015 Jun 27;2(8):874-83. doi: 10.1016/j.ebiom.2015.06.019. eCollection 2015 Aug.
2
The need for treatment interruption studies and biomarker identification in the search for an HIV cure.在寻找治愈艾滋病方法的过程中进行治疗中断研究和生物标志物识别的必要性。
AIDS. 2015 Jul 31;29(12):1429-32. doi: 10.1097/QAD.0000000000000658.
3
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption.治疗中断后，大量反弹/失活的HIV变异体在淋巴组织的多灶性感染中出现。
Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1126-34. doi: 10.1073/pnas.1414926112. Epub 2015 Feb 23.
4
Improved single-copy assays for quantification of persistent HIV-1 viremia in patients on suppressive antiretroviral therapy.改良的单拷贝检测法用于定量检测接受抑制性抗逆转录病毒治疗的患者体内持续性 HIV-1 病毒血症。
J Clin Microbiol. 2014 Nov;52(11):3944-51. doi: 10.1128/JCM.02060-14. Epub 2014 Sep 3.
5
Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases.异基因干细胞移植后无抗逆转录病毒治疗的HIV-1缓解及病毒反弹：2例报告
Ann Intern Med. 2014 Sep 2;161(5):319-27. doi: 10.7326/M14-1027.
6
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.潜伏库中具有复制能力的非诱导前病毒增加了 HIV-1 治愈的障碍。
Cell. 2013 Oct 24;155(3):540-51. doi: 10.1016/j.cell.2013.09.020.
7
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient.在可能治愈的干预措施期间检测 HIV 持续存在的挑战：柏林患者研究。
PLoS Pathog. 2013;9(5):e1003347. doi: 10.1371/journal.ppat.1003347. Epub 2013 May 9.
8
Cell-associated HIV RNA: a dynamic biomarker of viral persistence.细胞相关 HIV RNA：病毒持续存在的动态生物标志物。
Retrovirology. 2013 Apr 15;10:41. doi: 10.1186/1742-4690-10-41.
9
Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies.HIV-1 根除研究中病毒储存库测量方法的比较分析。
PLoS Pathog. 2013 Feb;9(2):e1003174. doi: 10.1371/journal.ppat.1003174. Epub 2013 Feb 14.
Zotero 插件