Maher W P
Cleft Palate J. 1977 Jan;14(1):1-12.
Cleft lip and cleft palate are two possible effects of fusion failure of embryonic facial processes. Aberrant facial morphogenesis suggest aberrant arterial distribution. Prompted by surgical need, studies detailing major branches of the third or pterygopalatine portion of the maxillary artery acquire practical significance. Therefore postomortem arteriographic studies were undertaken to ascertain location of these major arteries and their branches in twelve near-term human fetuses. Comparison was made between arterial distributions in three cleft and nine non-cleft fetal palates. The question of bilateral symmetry was examined. It is known that these major branches are commonly present on both sides, but the study revealed numberous variations in each facial half in both cleft and non-cleft palates. Variation implies morphologic contradiction with sterotype presentations. So numberous are the variations that occasionally they may account for sudden and unexpected hemorrhage during surgery/and retarded healing or sphacelus of flaps following surgery.
唇裂和腭裂是胚胎面部发育过程融合失败可能产生的两种后果。面部形态异常提示动脉分布异常。出于手术需要，详细研究上颌动脉第三段或翼腭段的主要分支具有实际意义。因此，进行了尸体血管造影研究，以确定这些主要动脉及其分支在12例近足月人类胎儿中的位置。对3例腭裂胎儿和9例非腭裂胎儿的动脉分布进行了比较。研究了双侧对称性问题。已知这些主要分支通常两侧都有，但研究发现，腭裂和非腭裂胎儿的每侧面部都有许多变异。变异意味着与典型表现存在形态学矛盾。变异如此之多，以至于它们偶尔可能导致手术期间突然和意外的出血，以及手术后皮瓣愈合延迟或坏死。
