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减重手术期间的常规肝活检:循证分析

Routine Liver Biopsy During Bariatric Surgery: an Analysis of Evidence Base.

作者信息

Mahawar Kamal K, Parmar Chetan, Graham Yitka, Abouleid Ayman, Carr William R J, Jennings Neil, Schroeder Norbert, Small Peter K

机构信息

Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.

Department of Pharmacy, Health and Well-being, University of Sunderland, Sunderland, SR1 3SD, UK.

出版信息

Obes Surg. 2016 Jan;26(1):177-81. doi: 10.1007/s11695-015-1916-z.

Abstract

Non-alcoholic fatty liver disease and non-alcoholic steato-hepatitis are common in patients undergoing bariatric surgery. Non-alcoholic steato-hepatitis can progress to cirrhosis of the liver and hepatocellular carcinoma. Non-invasive methods of diagnosing non-alcoholic steato-hepatitis are not as accurate as liver biopsy, and bariatric surgery presents a unique opportunity to carry out a simultaneous liver biopsy. Routine liver biopsy can help early and accurate diagnosis of obesity-associated liver conditions. This has led some surgeons to argue for routine liver biopsy at the time of bariatric surgery. However, most bariatric surgeons remain unconvinced and liver biopsy is currently not routine practice with bariatric surgery. This review examines published scientific literature to ascertain the usefulness of routine liver biopsy at the time of bariatric surgery.

摘要

非酒精性脂肪性肝病和非酒精性脂肪性肝炎在接受减肥手术的患者中很常见。非酒精性脂肪性肝炎可进展为肝硬化和肝细胞癌。非侵入性诊断非酒精性脂肪性肝炎的方法不如肝活检准确,而减肥手术提供了同时进行肝活检的独特机会。常规肝活检有助于早期准确诊断肥胖相关的肝脏疾病。这使得一些外科医生主张在减肥手术时进行常规肝活检。然而,大多数减肥外科医生仍未被说服,目前肝活检在减肥手术中并非常规操作。本综述查阅已发表的科学文献,以确定减肥手术时常规肝活检的实用性。

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