病毒进入
Viral Entry.
作者信息
Chesnokova Liudmila S, Jiang Ru, Hutt-Fletcher Lindsey M
机构信息
Department of Microbiology and Immunology, Center for Molecular and Tumor Virology, Feist-Weiller Cancer Center, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA.
Department of Clinical Teaching and Training, Tianjin University of Traditional Chinese Medicine, 312 West Anshan Road, 300193, Nankai District, Tianjin, China.
出版信息
Curr Top Microbiol Immunol. 2015;391:221-35. doi: 10.1007/978-3-319-22834-1_7.
Epstein-Barr virus primarily, though not exclusively, infects B cells and epithelial cells. Many of the virus and cell proteins that are involved in entry into these two cell types in vitro have been identified, and their roles in attachment and fusion are being explored. This chapter discusses what is known about entry at the cellular level in vitro and describes what little is known about the process in vivo. It highlights some of the questions that still need to be addressed and considers some models that need further testing.
爱泼斯坦-巴尔病毒主要（但并非唯一）感染B细胞和上皮细胞。许多在体外参与进入这两种细胞类型的病毒和细胞蛋白已被鉴定出来，并且它们在附着和融合中的作用正在被探索。本章讨论了在体外细胞水平上关于病毒进入的已知情况，并描述了在体内该过程的所知甚少之处。它强调了一些仍需解决的问题，并考虑了一些需要进一步测试的模型。
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