Yuh W T, Hunsicker L G, Sato Y, Wright F H, Smith J L, Corry R J
Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Diabetes. 1989 Jan;38 Suppl 1:27-9. doi: 10.2337/diab.38.1.s27.
Various imaging methods have been used in the differential diagnosis of pancreas-transplant dysfunction. As early as 1977, angiography and radionuclide studies ([75Se]seleno-DL-methionine) were used to evaluate pancreas allografts. More recently, the use of 99mTc-labeled DTPA, computed tomography, and ultrasonography has been described, and abnormal findings associated with rejection have been reported with these imaging methods. However, no attempt has been made to determine the ability of each method to detect rejection and to differentiate graft dysfunction caused by rejection from dysfunction by other causes. We summarize our experience with the application of magnetic resonance imaging (MRI) in pancreas transplantation and a comparative study of radionuclide 99mTc-DTPA scans, ultrasonography, and MRI in the detection and differentiation of pancreas-graft dysfunction.
多种成像方法已被用于胰腺移植功能障碍的鉴别诊断。早在1977年，血管造影和放射性核素研究（[75Se]硒代-DL-蛋氨酸）就被用于评估胰腺移植。最近，已经描述了使用99mTc标记的二乙三胺五乙酸（DTPA）、计算机断层扫描和超声检查，并且这些成像方法报告了与排斥反应相关的异常发现。然而，尚未有人尝试确定每种方法检测排斥反应以及区分由排斥反应引起的移植功能障碍与其他原因导致的功能障碍的能力。我们总结了我们在胰腺移植中应用磁共振成像（MRI）的经验，以及放射性核素99mTc-DTPA扫描、超声检查和MRI在检测和区分胰腺移植功能障碍方面的比较研究。
