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HIV 阳性成年人的非伤寒沙门氏菌感染

Non-typhoidal Salmonella infections in HIV-positive adults.

作者信息

Subramoney Evette L

机构信息

Department of Internal Medicine, Mahatma Gandhi Memorial Hospital, Durban, South Africa.

出版信息

S Afr Med J. 2015 Sep 18;105(10):805-7. doi: 10.7196/SAMJnew.7802.

Abstract

Non-typhoidal salmonellae are important pathogens causing bacteraemia, especially in immunocompromised patients, but there are limited data explicitly describing the clinical characteristics and outcome in these individuals. Recurrent invasive salmonellosis has been recognised as an AIDS-defining condition in HIV-positive patients since the 1980s. Salmonella meningitis is an infrequent complication of Salmonella sepsis, accounting for 0.8-6% of all cases of bacterial meningitis, and is associated with a high mortality rate.

摘要

非伤寒沙门氏菌是引起菌血症的重要病原体,尤其是在免疫功能低下的患者中,但明确描述这些个体临床特征和转归的数据有限。自20世纪80年代以来,复发性侵袭性沙门氏菌感染已被认定为HIV阳性患者的一种艾滋病界定疾病。沙门氏菌脑膜炎是沙门氏菌败血症的一种罕见并发症,占所有细菌性脑膜炎病例的0.8%-6%,且死亡率很高。

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