一名患有吉兰-巴雷综合征的HIV-1阳性患者的静脉注射免疫球蛋白治疗

Intravenous immunoglobulin treatment in a HIV-1 positive patient with Guillain-Barré syndrome.

作者信息

Rosca Elena Cecilia, Rosca Ovidiu, Simu Mihaela

机构信息

University of Medicine and Pharmacy "Victor Babes" Timisoara, Department of Neurology, Romania; Clinical Emergency County Hospital Timisoara, Department of Neurology, Romania.

University of Medicine and Pharmacy "Victor Babes" Timisoara, Department of Infectious Diseases, Romania.

出版信息

Int Immunopharmacol. 2015 Dec;29(2):964-965. doi: 10.1016/j.intimp.2015.09.023. Epub 2015 Oct 1.

DOI:10.1016/j.intimp.2015.09.023

PMID:26428850

Abstract

We report the case of an HIV-1 positive patient with primary demyelinating neuropathy (Guillain-Barré syndrome); after intravenous immunoglobulin treatment (IVIG), he presented with an increase in CD4 and CD8 cell counts and a decrease in plasma viral load. Currently, there is little reported research regarding IVIG treatment in adults with HIV-1. The present report brings further evidence regarding the possible benefit of IVIG in HIV-1 infected patients, providing a novel perspective on treatment.

摘要

我们报告了一例患有原发性脱髓鞘性神经病（吉兰-巴雷综合征）的HIV-1阳性患者；在接受静脉注射免疫球蛋白治疗（IVIG）后，他的CD4和CD8细胞计数增加，血浆病毒载量降低。目前，关于IVIG治疗成人HIV-1感染的报道研究很少。本报告为IVIG对HIV-1感染患者可能的益处提供了进一步的证据，为治疗提供了新的视角。