Sun Baozhou, Goddu S Murty, Yaddanapudi Sridhar, Noel Camille, Li Hua, Cai Bin, Kavanaugh James, Mutic Sasa
Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, Campus Box 8224, St. Louis, Missouri 63110.
Med Phys. 2015 Oct;42(10):5584-94. doi: 10.1118/1.4929550.
As treatment delivery becomes more complex, there is a pressing need for robust quality assurance (QA) tools to improve efficiency and comprehensiveness while simultaneously maintaining high accuracy and sensitivity. This work aims to present the hardware and software tools developed for comprehensive QA of linear accelerator (LINAC) using only electronic portal imaging devices (EPIDs) and kV flat panel detectors.
A daily QA phantom, which includes two orthogonally positioned phantoms for QA of MV-beams and kV onboard imaging (OBI) is suspended from the gantry accessory holder to test both geometric and dosimetric components of a LINAC and an OBI. The MV component consists of a 0.5 cm water-equivalent plastic sheet incorporating 11 circular steel plugs for transmission measurements through multiple thicknesses and one resolution plug for MV-image quality testing. The kV-phantom consists of a Leeds phantom (TOR-18 FG phantom supplied by Varian) for testing low and high contrast resolutions. In the developed process, the existing LINAC tools were used to automate daily acquisition of MV and kV images and software tools were developed for simultaneous analysis of these images. A method was developed to derive and evaluate traditional QA parameters from these images [output, flatness, symmetry, uniformity, TPR20/10, and positional accuracy of the jaws and multileaf collimators (MLCs)]. The EPID-based daily QA tools were validated by performing measurements on a detuned 6 MV beam to test its effectiveness in detecting errors in output, symmetry, energy, and MLC positions. The developed QA process was clinically commissioned, implemented, and evaluated on a Varian TrueBeam LINAC (Varian Medical System, Palo Alto, CA) over a period of three months.
Machine output constancy measured with an EPID (as compared against a calibrated ion-chamber) is shown to be within ±0.5%. Beam symmetry and flatness deviations measured using an EPID and a 2D ion-chamber array agree within ±0.5% and ±1.2% for crossline and inline profiles, respectively. MLC position errors of 0.5 mm can be detected using a picket fence test. The field size and phantom positioning accuracy can be determined within 0.5 mm. The entire daily QA process takes ∼15 min to perform tests for 5 photon beams, MLC tests, and imaging checks.
The exclusive use of EPID-based QA tools, including a QA phantom and simultaneous analysis software tools, has been demonstrated as a viable, efficient, and comprehensive process for daily evaluation of LINAC performance.
随着治疗交付变得更加复杂,迫切需要强大的质量保证(QA)工具来提高效率和全面性,同时保持高精度和高灵敏度。这项工作旨在介绍仅使用电子射野影像装置(EPID)和千伏平板探测器开发的用于直线加速器(LINAC)全面QA的硬件和软件工具。
一个每日QA体模,包括两个正交放置的体模,用于兆伏级射线束和千伏级机载成像(OBI)的QA,从机架附件支架上悬挂下来,以测试直线加速器和OBI的几何和剂量学组件。兆伏级组件由一块0.5厘米水等效塑料板组成,其中包含11个圆形钢塞用于多种厚度的透射测量,以及一个分辨率塞用于兆伏级图像质量测试。千伏级体模由一个利兹体模(瓦里安提供的TOR-18 FG体模)组成,用于测试低对比度和高对比度分辨率。在开发过程中,使用现有的直线加速器工具自动每日采集兆伏级和千伏级图像,并开发软件工具用于同时分析这些图像。开发了一种方法,从这些图像中推导和评估传统QA参数[输出、平坦度、对称性、均匀性、TPR20/10以及准直器和多叶准直器(MLC)的位置精度]。通过在失谐的6兆伏级射线上进行测量来验证基于EPID的每日QA工具,以测试其在检测输出、对称性、能量和MLC位置误差方面的有效性。在瓦里安TrueBeam直线加速器(瓦里安医疗系统公司,加利福尼亚州帕洛阿尔托)上对开发的QA过程进行了为期三个月的临床调试、实施和评估。
用EPID测量的机器输出稳定性(与校准的电离室相比)显示在±0.5%以内。使用EPID和二维电离室阵列测量的射束对称性和平坦度偏差,对于交叉线和直线剖面,分别在±0.5%和±1.2%以内一致。使用栅栏测试可以检测到0.5毫米的MLC位置误差。射野尺寸和体模定位精度可以在0.5毫米内确定。整个每日QA过程对5个光子束、MLC测试和成像检查进行测试大约需要15分钟。
已证明仅使用基于EPID的QA工具,包括QA体模和同时分析软件工具,是一种可行、高效且全面的每日评估直线加速器性能的过程。