Joslin Jennifer, Wilson Hannah, Zubli Daniel, Gauge Nathan, Kinirons Mark, Hopper Adrian, Pile Taryn, Ostermann Marlies
Guy's and St Thomas' NHS Foundation Hospital, London, UK.
General and Geriatric Medicine, Guy's and St Thomas' NHS Foundation Hospital, London, UK.
Clin Med (Lond). 2015 Oct;15(5):431-6. doi: 10.7861/clinmedicine.15-5-431.
Acute kidney injury (AKI) is common in hospitalised patients but is known be suboptimally managed; the National Confidential Enquiry into Patient Outcomes and Death (NCEPOD) report in 2009 identified significant failings in AKI care. An audit, using standards suggested by the NCEPOD report, of all adult inpatients with AKI in a large central-London NHS hospital in a 7-day period in 2011 showed poor recognition and management of AKI. In response, an AKI 'care bundle' was developed and deployed throughout the hospital along with a programme of enhanced education. Re-audit in 2013 showed that AKI was significantly more likely to have been recognised by the clinical team than in 2011, and patients with AKI were significantly more likely to have had fluid status clinically assessed and nephrotoxic medication stopped in 2013 than in 2011. There was no significant improvement in fluid administration if assessed as hypovolaemic and compliance with the guideline for prevention of contrast nephropathy. In 2011, all audit measures were met in 3.7% of patient-days versus 8.4% in 2013. More in-depth work is necessary to better understand the factors which limit optimal care.
急性肾损伤(AKI)在住院患者中很常见,但已知其治疗效果欠佳;2009年的《全国患者结局与死亡保密调查报告》(NCEPOD)指出急性肾损伤护理存在重大缺陷。2011年,一家位于伦敦市中心的大型国民保健服务(NHS)医院,按照NCEPOD报告建议的标准,对所有成年急性肾损伤住院患者进行了为期7天的审核,结果显示对急性肾损伤的识别和管理较差。作为回应,医院制定了急性肾损伤“护理套餐”,并在全院推行,同时开展了强化教育项目。2013年的再次审核显示,与2011年相比,临床团队识别急性肾损伤的可能性显著增加,而且2013年急性肾损伤患者接受临床液体状态评估以及停用肾毒性药物的可能性也显著高于2011年。如果评估为血容量不足,在液体管理方面以及在预防造影剂肾病指南的依从性方面均无显著改善。2011年,3.7%的患者日达到了所有审核指标,而2013年这一比例为8.4%。有必要开展更深入的工作,以更好地了解限制最佳治疗的因素。