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钙质沉着症、雷诺现象、食管动力障碍、指(趾)硬皮病和毛细血管扩张综合征患者腿部肌肉的营养不良性钙化:用(99m)锝-亚甲基二膦酸盐单光子发射计算机断层扫描/计算机断层扫描准确评估其范围

Dystrophic calcification in muscles of legs in calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia syndrome: Accurate evaluation of the extent with (99m)Tc-methylene diphosphonate single photon emission computed tomography/computed tomography.

作者信息

Chakraborty Partha Sarathi, Karunanithi Sellam, Dhull Varun Singh, Kumar Kunal, Tripathi Madhavi

机构信息

Department of Nuclear Medicine, All Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Nucl Med. 2015 Oct-Dec;30(4):360-1. doi: 10.4103/0972-3919.159695.

Abstract

We present the case of a 35-year-old man with calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia variant scleroderma who presented with dysphagia, Raynaud's phenomenon and calf pain. (99m)Tc-methylene diphosphonate bone scintigraphy was performed to identify the extent of the calcification. It revealed extensive dystrophic calcification in the left thigh and bilateral legs which was involving the muscles and was well-delineated on single photon emission computed tomography/computed tomography. Calcinosis in scleroderma usually involves the skin but can be found in deeper periarticular tissues. Myopathy is associated with a poor prognosis.

摘要

我们报告一例35岁男性患者,患有钙质沉着、雷诺现象、食管动力障碍、指(趾)硬皮病和毛细血管扩张型硬皮病,表现为吞咽困难、雷诺现象和小腿疼痛。进行了(99m)锝-亚甲基二膦酸盐骨闪烁显像以确定钙化范围。结果显示左大腿和双侧小腿广泛的营养不良性钙化,累及肌肉,在单光子发射计算机断层扫描/计算机断层扫描上清晰可见。硬皮病中的钙质沉着通常累及皮肤,但也可出现在更深层的关节周围组织。肌病与预后不良相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff9/4579629/ed96e2cf44ef/IJNM-30-360-g001.jpg

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