Basit Shahla, Karim Nasim, Munshi Alia Bano
Shahla Basit, MBBS Principal Medical Officer.
Nasim Karim, FCPS.PHD Professor and Head Pharmacology Department, Bahria University Medical & Dental College, Karachi, Pakistan.
Pak J Med Sci. 2015 Jul-Aug;31(4):775-80. doi: 10.12669/pjms.314.7066.
To estimate blood lead level (BLL) and to assess the features of lead toxicity among lead acid battery (LAB) industrial workers.
This prospective study was carried out in the medical centre of PCSIR Laboratories, Karachi from March 2012 - March 2013. Fifty LAB industry workers, males and females between 17-65 years were included in the study. They were divided into group 1 with 40 workers- directly related and group 2 with 10 workers -indirectly related, (administration staff members) to LAB manufacture. Detailed history, complete physical examination and BLL estimation by flameless atomic absorption spectrophotometer was done.
Total 34 patients in group 1 and 3 patients in group 2 had elevated BLL. Comparison of group 1 and 2 revealed anemia (40v/s4), bone pain (38v/s7), abdominal pain (38 v/s 2), nausea (32v/s6), head ache & irritability (24v/s6), weakness & lethargy (21v/s6), tremors (13v/s0) insomnia (5v/s4), lead line (4v/s 0) and blood pressure above 140/90 mm of Hg (12v/s0) respectively.
High blood lead level and features attributable to lead toxicity were prevalent among LAB industry workers of Karachi.
评估铅酸蓄电池(LAB)产业工人的血铅水平(BLL)并分析铅中毒特征。
这项前瞻性研究于2012年3月至2013年3月在卡拉奇PCSIR实验室医学中心开展。研究纳入了50名年龄在17 - 65岁之间的LAB产业工人,男女皆有。他们被分为两组,第1组有40名工人,与LAB制造直接相关;第2组有10名工人,与LAB制造间接相关(行政工作人员)。研究人员详细询问了病史,进行了全面的体格检查,并通过无火焰原子吸收分光光度计测定了血铅水平。
第1组共有34名患者血铅水平升高,第2组有3名患者血铅水平升高。第1组和第2组的对比结果显示,两组出现贫血症状的患者分别为40例和4例,骨痛分别为38例和7例,腹痛分别为38例和2例,恶心分别为32例和6例,头痛及易怒分别为24例和6例,虚弱及嗜睡分别为21例和6例,震颤分别为13例和0例,失眠分别为5例和4例,铅线分别为4例和0例,血压高于140/90 mmHg的患者分别为12例和0例。
卡拉奇LAB产业工人中普遍存在高血铅水平及铅中毒相关特征。