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输血对骨科手术中肾功能的影响。

The effects of blood transfusion on renal functions in orthopaedic surgery.

作者信息

Satoglu Ismail Safa, Akcay Serkan, Horoz Levent, Kaya Erol, Karakasli Ahmet, Skiak Eyad, Basci Onur

机构信息

Ismail Safa Satoglu, Department of Orthopaedics & Traumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey.

Serkan Akcay, Department of Orthopaedics & Traumatology, Kurtköy Ersoy Hospital, Istanbul, Turkey.

出版信息

Pak J Med Sci. 2015 Jul-Aug;31(4):787-90. doi: 10.12669/pjms.314.7884.

DOI:10.12669/pjms.314.7884
PMID:26430403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4590404/
Abstract

OBJECTIVE

The effects of perioperative blood transfusion on renal functions have been studied in various studies. In this study, we investigated the effects of blood transfusion on postoperative kidney functions in patients who underwent orthopaedic surgeries.

METHOD

Total 136 patients who were operated for several orthopedic pathologies between June 2013 and December 2014 were evaluated. The patients were divided into two groups according to the amounts of blood transfusion. Ninety five patients (69.8%) who were transfused less than 3 units were included in Group 1 and 41 patients (30.2%) who received 3 and more units of blood were included in Group 2.

RESULTS

There were no statistical difference between the two groups in terms of preoperative gender, hypertension, diabetes mellitus, chronical renal failure and smoking habbits (P > 0.05). No statistical differences between the groups were seen in terms of postoperative hospital stay, pulmonary and other complications as well as mortality (P > 0.05). When the two groups were compared for blood parameters showing postoperative renal and other system functions, no statistical differences were detected (P > 0.05).

CONCLUSION

Blood transfusion does not have negative effects on postoperative BUN and creatinine levels in patients operated for orthopaedic pathologies.

摘要

目的

多项研究探讨了围手术期输血对肾功能的影响。在本研究中,我们调查了输血对接受骨科手术患者术后肾功能的影响。

方法

对2013年6月至2014年12月期间因多种骨科疾病接受手术的136例患者进行评估。根据输血量将患者分为两组。第1组包括95例(69.8%)输血量少于3单位的患者,第2组包括41例(30.2%)接受3单位及以上输血的患者。

结果

两组患者在术前性别、高血压、糖尿病、慢性肾衰竭和吸烟习惯方面无统计学差异(P>0.05)。两组在术后住院时间、肺部及其他并发症以及死亡率方面无统计学差异(P>0.05)。比较两组显示术后肾脏及其他系统功能的血液参数时,未检测到统计学差异(P>0.05)。

结论

输血对接受骨科手术的患者术后血尿素氮和肌酐水平没有负面影响。

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引用本文的文献

1
The effect of perioperative blood transfusion on kidney functions in total knee Arthroplasty.全膝关节置换术中围手术期输血对肾功能的影响。
Pak J Med Sci. 2019;35(3):663-667. doi: 10.12669/pjms.35.3.259.

本文引用的文献

1
Perioperative blood transfusions in orthopaedic surgery.骨科手术中的围手术期输血。
J Bone Joint Surg Am. 2014 Nov 5;96(21):1836-44. doi: 10.2106/JBJS.N.00128.
2
Transfusion-associated circulatory overload (TACO) and potential risk factors among the inpatient US elderly as recorded in Medicare administrative databases during 2011.2011 年美国老年住院患者医疗保险管理数据库中记录的输血相关循环超负荷(TACO)和潜在危险因素。
Vox Sang. 2014 Feb;106(2):144-52. doi: 10.1111/vox.12070. Epub 2013 Jul 12.
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The prevention of transfusion-associated circulatory overload.输血相关性循环超负荷的预防。
Transfus Med Rev. 2013 Apr;27(2):105-12. doi: 10.1016/j.tmrv.2013.02.001. Epub 2013 Mar 1.
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Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment.目前对过敏输血反应的认识:发生率、发病机制、实验室检查、预防和治疗。
Br J Haematol. 2013 Feb;160(4):434-44. doi: 10.1111/bjh.12150. Epub 2012 Dec 6.
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Risk of adverse outcomes associated with blood transfusion after cardiac surgery depends on the amount of transfusion.心脏手术后输血相关不良结局的风险取决于输血量。
J Surg Res. 2010 Jan;158(1):20-7. doi: 10.1016/j.jss.2008.10.015.
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Attitudes to blood transfusion post arthroplasty surgery in the United Kingdom: a national survey.英国人工关节置换术后输血态度:一项全国性调查。
Int Orthop. 2008 Jun;32(3):325-9. doi: 10.1007/s00264-007-0330-0. Epub 2007 Mar 30.
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Effect of peri-operative red blood cell transfusion on 30-day and 1-year mortality following coronary artery bypass surgery.围手术期红细胞输注对冠状动脉搭桥手术后30天和1年死亡率的影响。
Eur J Cardiothorac Surg. 2005 Apr;27(4):592-8. doi: 10.1016/j.ejcts.2005.01.030.
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Risk for postoperative infection after transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty.在接受初次关节置换术的骨科患者中,输注经白细胞过滤的异体或自体血液成分后发生术后感染的风险。
Transfusion. 2005 Jan;45(1):103-10. doi: 10.1111/j.1537-2995.2005.04149.x.
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A strategy for reducing blood-transfusion requirements in elective orthopaedic surgery. Audit of an algorithm for arthroplasty of the lower limb.
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Current and emerging infectious risks of blood transfusions.输血当前及新出现的感染风险。
JAMA. 2003 Feb 26;289(8):959-62. doi: 10.1001/jama.289.8.959.