Sen Baran, Ozmanevra Ramadan
Dr. Baran Sen, Department of Orthopaedics and Trauma Surgery, Cesme State Hospital, Izmir, Turkey.
Dr. Ramadan Ozmanevra, Department of Orthopaedics and Trauma Surgery, University of Kyrenia, Kyrenia, Northern Cyprus.
Pak J Med Sci. 2019;35(3):663-667. doi: 10.12669/pjms.35.3.259.
Various studies have examined the effects of perioperative blood transfusion on kidney functions. In this study, we investigated the effects of blood transfusion on the kidney functions of patients undergoing total knee arthroplasty.
: This retrospective study was carried out on 216 patients who had undergone total knee arthroplasty between January 2016 and January 2017. The patients were divided into two groups according to the level of blood transfusion used during surgery. Group-1 comprised 157 patients (72.7%) needing a blood transfusion of less than three units, while the 59 (27.3) patients in Group-2 required three or more than three units.
No statistical difference was found between the two groups regarding hypertension before surgery, diabetes mellitus, chronic kidney failure, smoking habits or lung disease (p> 0.05). Likewise, there was no significant difference related to pulmonary and other complications or mortality (p> 0.05). When the groups were compared according to their blood parameters, no statistical differences in postoperative renal or other system functions were found (p> 0.05).
Blood transfusion does not have a negative effect on postoperative blood urea nitrogen (BUN) and creatinine levels, or glomerular filtration rate in total knee arthroplasty.
多项研究探讨了围手术期输血对肾功能的影响。在本研究中，我们调查了输血对接受全膝关节置换术患者肾功能的影响。
本回顾性研究对2016年1月至2017年1月期间接受全膝关节置换术的216例患者进行。根据手术期间输血水平将患者分为两组。第一组包括157例（72.7%）输血少于3单位的患者，而第二组的59例（27.3%）患者需要3单位或更多单位的输血。
两组在术前高血压、糖尿病、慢性肾衰竭、吸烟习惯或肺部疾病方面无统计学差异（p>0.05）。同样，在肺部及其他并发症或死亡率方面也无显著差异（p>0.05）。当根据血液参数对两组进行比较时，术后肾脏或其他系统功能无统计学差异（p>0.05）。
输血对全膝关节置换术后的血尿素氮（BUN）、肌酐水平或肾小球滤过率没有负面影响。
