Motaqhey Monireh, Ghanjal Ali, Mastri Farahani Reza, Ghabaee Mojdeh, Kaka Gholamreza, Noroziyan Mohsen, Fadaee Fathabadi Fatemeh
Department of Anatomy and Cell Biology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Health Management Research Centre, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
Iran Red Crescent Med J. 2015 Aug 24;17(8):e28363. doi: 10.5812/ircmj.28363. eCollection 2015 Aug.
Considering the higher activity of mirror neuron system in females, they frequently have better performance in empathy, interpersonal sensitivity, and emotional recognition compared to males.
The purpose of this study was to assess whether gender difference in neuroanatomy of the human mirror neuron system has any impact on functional recovery of ischemic hemiparetic patients.
This single-blind clinical trial was conducted on 24 patients with cerebrovascular accident (CVA) in the age range of 45 - 60 years, referring at a rehabilitation center in Tehran, Iran, during 2013 - 2014. Sampling method was stratified random sampling. The subjects were assigned to 2 groups of 12 males and 12 females. Then, each group was randomly divided into 2 groups (totally 4 groups, n = 6 for each group): women watching functional movies, control women, men watching functional movies, and control men. Movies were shown to patients and then, they were evaluated by Timed Up and Go (TUG), Six-minute walk test (SMW), Barthel index (BI), and Berg balance scale (BBS).
Comparison of all variables related to functional activities of all groups before and after watching movies revealed significant differences. The highest percentage of change and improvement was observed in groups 1 and 3 watching the functional movies (P = 0.0001). Percentage of improvement in women of groups 1 and 2 was higher than men in groups 3 and 4 (P = 0.0003). The changes in group of females watching the functional movies (group 1) were significantly greater than in other groups (P < 0.0001).
The Sex differences in the neuroanatomy of the human mirror neuron system affect functional recovery of patients with hemiparesis. The improvement in studied women was found to be significantly greater than studied men. The results indicate a higher chance of recovery among hemiparetic women, especially those watching functional movies.
鉴于女性镜像神经元系统的活性较高，与男性相比，她们在同理心、人际敏感性和情绪识别方面的表现通常更好。
本研究旨在评估人类镜像神经元系统神经解剖结构中的性别差异是否对缺血性偏瘫患者的功能恢复有任何影响。
本单盲临床试验于2013 - 2014年在伊朗德黑兰一家康复中心对24名年龄在45 - 60岁的脑血管意外（CVA）患者进行。抽样方法为分层随机抽样。受试者被分为两组，每组12名男性和12名女性。然后，每组再随机分为两组（共4组，每组n = 6）：观看功能电影的女性、对照女性、观看功能电影的男性和对照男性。向患者播放电影，然后通过定时起立行走测试（TUG）、六分钟步行测试（SMW）、巴氏指数（BI）和伯格平衡量表（BBS）对他们进行评估。
比较所有组在观看电影前后与功能活动相关的所有变量，发现存在显著差异。在观看功能电影的第1组和第3组中观察到最高的变化和改善百分比（P = 0.0001）。第1组和第2组女性的改善百分比高于第3组和第4组男性（P = 0.0003）。观看功能电影的女性组（第1组）的变化明显大于其他组（P < 0.0001）。
人类镜像神经元系统神经解剖结构中的性别差异影响偏瘫患者的功能恢复。研究发现，所研究的女性的改善明显大于男性。结果表明偏瘫女性，尤其是观看功能电影的女性，恢复的机会更高。
