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术前血球比容水平对腰椎手术后住院时间的影响。

Impact of Preoperative Hematocrit Level on Length of Stay after Surgery on the Lumbar Spine.

机构信息

Department of Neurosurgery, University of Utah, Salt Lake City, Utah, United States.

出版信息

Global Spine J. 2015 Oct;5(5):391-5. doi: 10.1055/s-0035-1550090. Epub 2015 Apr 29.

DOI:10.1055/s-0035-1550090
PMID:26430593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4577325/
Abstract

Study Design Retrospective case series. Objective Recent studies suggest that baseline hematocrit (Hct) levels may affect the surgical outcomes after orthopedic procedures. The authors examined whether preoperative Hct values had a significant effect on the hospital length of stay (LoS) after lumbar spinal procedures. Methods We retrospectively reviewed patients who underwent routine lumbar spine procedures from November 2012 through September 2013. Patients were included if they had both a baseline Hct and hospital LoS recorded. Patients were divided into two groups: those with an Hct ≥ 40% (nonanemic) and those with an Hct < 40% (anemic). LoS after surgery was evaluated for each group. Results One hundred seventeen patients underwent lumbar spine procedures for lumbar stenosis (n = 34), symptomatic lumbar disk herniation (n = 39), lumbar spondylolisthesis (n = 26), lumbar adjacent segment disease (n = 8), or symptomatic recurrent lumbar disk herniation (n = 10). Mean LoS was 3.3 and 2.4 days in anemic (27 patients) and nonanemic groups (90 patients), respectively (p = 0.02). The linear regression analysis demonstrated that a decrease in Hct was associated with a longer stay. A decrease from preoperative to postoperative day 1 Hct of 3.5 points resulted in an increased LoS of 1 day (R (2) = 0.145; p = 0.002). The correlation of Hct decrease with longer LoS remained (β = 0.167, p = 0.006) after adjusting for other variables with multivariate regression analysis. Conclusions Lower preoperative Hct or a substantial decrease in Hct may contribute to longer hospitalization after lumbar spine surgery. These findings should prompt an investigation into the strategies for optimizing Hct levels in patients with preoperative anemia prior to lumbar spine procedures.

摘要

研究设计

回顾性病例系列研究。目的:最近的研究表明,基线血细胞比容(Hct)水平可能会影响骨科手术后的手术结果。作者检查了术前 Hct 值是否对腰椎手术后的住院时间(LoS)有显著影响。方法:我们回顾性分析了 2012 年 11 月至 2013 年 9 月期间接受常规腰椎手术的患者。如果患者同时记录了基线 Hct 和住院 LoS,则将其纳入研究。患者分为两组:Hct≥40%(非贫血)和 Hct<40%(贫血)。评估每组手术后的 LoS。结果:117 例患者因腰椎管狭窄症(n=34)、症状性腰椎间盘突出症(n=39)、腰椎滑脱症(n=26)、腰椎相邻节段疾病(n=8)或症状性复发性腰椎间盘突出症(n=10)接受腰椎手术。贫血组(27 例)和非贫血组(90 例)的平均 LOS 分别为 3.3 天和 2.4 天(p=0.02)。线性回归分析表明,Hct 的降低与住院时间延长有关。术前至术后第 1 天 Hct 下降 3.5 个单位会导致住院时间延长 1 天(R²=0.145;p=0.002)。多元回归分析调整其他变量后,Hct 下降与 LOS 延长的相关性仍然存在(β=0.167,p=0.006)。结论:术前 Hct 较低或 Hct 明显下降可能导致腰椎手术后住院时间延长。这些发现应该促使人们调查在腰椎手术前针对术前贫血患者优化 Hct 水平的策略。