Jung Bok Ki, Nahm Ji Hae, Lew Dae Hyun, Lee Dong Won
Institute for Human Tissue Restoration, Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, Korea.
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Arch Plast Surg. 2015 Sep;42(5):630-4. doi: 10.5999/aps.2015.42.5.630. Epub 2015 Sep 15.
Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign mesenchymal lesion with incidental histologic findings. Surgical excision is recommended as the treatment of choice for PASH, although the recurrence rates after excision range from 15% to 22%. A 46-year-old-female presented with a six-month history of bilateral breast enlargement and painful sensation mimicking inflammatory carcinoma. Imaging studies demonstrated innumerable enhancing nodules in both breasts. Due to the growth of the lesions and progressive clinical symptoms, bilateral subcutaneous mastectomy was performed. Grossly, the specimens were round and well-circumscribed, and the histologic examination revealed PASH. After mastectomy, we created a pocket with the pectoralis major muscle and a lower skin flap, which was deepithelized. Anatomical mammary implants were inserted, and the nipple areolar complex was transferred to a new position as a free graft. The aesthetic result was satisfactory after twelve months of follow-up.
乳腺假血管瘤样间质增生(PASH)是一种具有偶然组织学表现的良性间质性病变。尽管切除术后复发率在15%至22%之间,但手术切除仍被推荐为PASH的首选治疗方法。一名46岁女性出现双侧乳房增大伴疼痛6个月,症状类似炎性癌。影像学检查显示双侧乳房有无数强化结节。由于病变生长及临床症状逐渐加重,遂行双侧皮下乳房切除术。大体上,标本呈圆形,边界清晰,组织学检查显示为PASH。乳房切除术后,我们利用胸大肌和去上皮化的下部皮瓣形成一个腔隙。植入解剖型乳房假体,并将乳头乳晕复合体作为游离移植物转移至新位置。随访12个月后,美学效果令人满意。