Department of Surgery, Hata General Hospital, 4417-180 Hata, Nagano, 390-1401, Japan.
Breast Cancer. 2013 Apr;20(2):187-90. doi: 10.1007/s12282-009-0188-7. Epub 2010 Jan 14.
Pseudoangiomatous stromal hyperplasia (PASH), characterized by the presence of slit-like spaces embedded in a hyalinized stroma, is sometimes observed during pathologic examination of breast-tissue specimens. Because tumor-forming PASH is rare, we report a case of a 41-year-old woman admitted to our hospital with a tumor in her left breast. Ultrasonography and aspiration biopsy cytology revealed a benign tumor. After performing Mammotome(®) biopsy, the lesion was diagnosed as PASH of the breast based on characteristic findings of histology and immunohistochemical studies. Because PASH tumors do not usually become malignant, we decided to perform ultrasonographic follow-up without tumor excision.
假血管瘤样间质增生（PASH）的特征是存在嵌入在玻璃样基质中的裂隙样空间，在乳腺组织标本的病理检查中有时会观察到。由于形成肿瘤的 PASH 很少见，我们报告了 1 例 41 岁女性，因左乳肿瘤入院。超声和抽吸活检细胞学显示为良性肿瘤。在进行 Mammotome（®）活检后，根据组织学和免疫组织化学研究的特征性发现，诊断为乳腺 PASH。由于 PASH 肿瘤通常不会恶变，我们决定进行超声随访而不切除肿瘤。
