Stephen Andrew H, Fallon Eleanor A, Kalife Elizabeth, Wanebo Harold
Department of Surgery, Alpert Medical School of Brown University, Providence, Rhode Island.
Department of Pathology, Alpert Medical School of Brown University, Providence, Rhode Island.
J Surg Oncol. 2015 Nov;112(6):658-61. doi: 10.1002/jso.24059. Epub 2015 Oct 2.
Radiation associated sarcoma is a significant consequence of cancer therapy. Incidence of radiation associated sarcoma correlates with overall radiotherapy exposure. Prognosis is generally poor with 5 year survival rates lower than that for spontaneously occurring sarcomas. Surgical management presents many challenges including having to work in irradiated tissue planes while trying to achieve negative margins. We present a patient with a rare radiation associated pelvic sarcoma whose course illustrates the complexity of this problem.
放射性相关肉瘤是癌症治疗的一个重要后果。放射性相关肉瘤的发病率与总体放疗暴露量相关。其预后通常较差，5年生存率低于自发发生的肉瘤。手术治疗面临许多挑战，包括在放疗后的组织层面进行操作，同时试图实现切缘阴性。我们报告一例罕见的放射性相关盆腔肉瘤患者，其病程说明了这个问题的复杂性。
