Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, HPL H36, 8093 Zurich, Switzerland.
Mol Cell. 2015 Oct 1;60(1):4-6. doi: 10.1016/j.molcel.2015.09.014.
In this issue, Fang and Bartel (2015) report the identification of novel sequence and structural features of human pri-miRNAs, which--together with previously identified sequence motifs--define a unifying model of mammalian pri-miRNAs and advances the de novo design of artificial pri-miRNAs.
本期中，Fang 和 Bartel（2015）报道了对人类前体 miRNA 的新型序列和结构特征的鉴定，这些特征与先前鉴定的序列基序一起，定义了哺乳动物前体 miRNA 的统一模型，并推进了人工前体 miRNA 的从头设计。
