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白内障手术后眼压的变化:瑞典国家白内障登记数据的分析

Changes in intraocular pressure after cataract surgery: analysis of the Swedish National Cataract Register Data.

作者信息

Zetterström Charlotta, Behndig Anders, Kugelberg Maria, Montan Per, Lundström Mats

机构信息

From the Department of Clinical Neuroscience (Zetterström, Kugelberg, Montan), Division of Ophthalmology and Vision, Karolinska Institutet, and EyeNet Sweden (Zetterström, Lundström), Blekinge Hospital, Karolinska; St. Erik Eye Hospital (Kugelberg, Montan), Stockholm; the Department of Clinical Sciences/Ophthalmology (Behndig), Umeå University Hospital, Umeå; and the Department of Clinical Sciences (Lundström) Ophthalmology, Faculty of Medicine, Lund University, Lund, Sweden.

From the Department of Clinical Neuroscience (Zetterström, Kugelberg, Montan), Division of Ophthalmology and Vision, Karolinska Institutet, and EyeNet Sweden (Zetterström, Lundström), Blekinge Hospital, Karolinska; St. Erik Eye Hospital (Kugelberg, Montan), Stockholm; the Department of Clinical Sciences/Ophthalmology (Behndig), Umeå University Hospital, Umeå; and the Department of Clinical Sciences (Lundström) Ophthalmology, Faculty of Medicine, Lund University, Lund, Sweden.

出版信息

J Cataract Refract Surg. 2015 Aug;41(8):1725-9. doi: 10.1016/j.jcrs.2014.12.054.

Abstract

PURPOSE

To analyze changes in intraocular pressure (IOP) after cataract surgery based on data from the Swedish National Cataract Register (NCR).

SETTING

Ophthalmic surgery units in Sweden.

DESIGN

Prospective database study.

METHODS

Data for 2012 through 2014 were obtained prospectively from the NCR. The outcome register of the NCR has collected data on IOP before and a mean of 37.7 days ± 29.1 (SD) after cataract surgery since 2012.

RESULTS

The analyses were based on 20 437 cataract extractions reported during 1 month each year to the outcome registry of the NCR. Cataract surgery was found to reduce IOP by a mean of 1.46 mm Hg, which was statistically significant (P < .001). A larger IOP reduction was seen in cases with a higher preoperative IOP (r = 0.557, P < .001). Older patients and shorter eyes had a greater IOP reduction after surgery (P < .001 and P = .001, respectively). Women had a greater IOP reduction than men (P = .04) When high IOP was given as an indication for surgery, the IOP reduction after cataract surgery was 5.50 mm Hg compared with a reduction of 1.40 mm Hg in patients for whom this indication was not given (P < .001). Patients with glaucoma or pseudoexfoliation (PXF) had a more pronounced IOP reduction than patients without these diagnoses (P < .001).

CONCLUSION

Cataract surgery had an IOP-lowering effect, in particular in older patients, women, short eyes, eyes with high preoperative IOP, and eyes with glaucoma or PXF.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

基于瑞典国家白内障登记处(NCR)的数据,分析白内障手术后眼压(IOP)的变化。

地点

瑞典的眼科手术单位。

设计

前瞻性数据库研究。

方法

前瞻性地从NCR获取2012年至2014年的数据。自2012年以来,NCR的结果登记处收集了白内障手术前及术后平均37.7天±29.1(标准差)的眼压数据。

结果

分析基于每年向NCR结果登记处报告的1个月内的20437例白内障摘除术。发现白内障手术可使眼压平均降低1.46 mmHg,具有统计学意义(P <.001)。术前眼压较高的病例眼压降低幅度更大(r = 0.557,P <.001)。老年患者和眼轴较短的患者术后眼压降低幅度更大(分别为P <.001和P =.001)。女性的眼压降低幅度大于男性(P =.04)。当以高眼压作为手术指征时,白内障手术后眼压降低5.50 mmHg,而未以此为手术指征的患者眼压降低1.40 mmHg(P <.001)。患有青光眼或假性剥脱(PXF)的患者眼压降低比未诊断出这些疾病的患者更明显(P <.001)。

结论

白内障手术具有降低眼压的作用,尤其是在老年患者、女性、眼轴短的患者、术前眼压高的患者以及患有青光眼或PXF的患者中。

财务披露

没有作者对文中提及的任何材料或方法拥有财务或专利权益。

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