Deol Madhvi, Ehrlich Joshua R, Shimmyo Mitsugu, Radcliffe Nathan M
From the Departments of Ophthalmology, Weill Medical College, Cornell University, and New York University School of Medicine, New York, and New York Medical College, Valhalla, New York, and the Wills Eye Institute, Philadelphia, Pennsylvania, USA.
From the Departments of Ophthalmology, Weill Medical College, Cornell University, and New York University School of Medicine, New York, and New York Medical College, Valhalla, New York, and the Wills Eye Institute, Philadelphia, Pennsylvania, USA.
J Cataract Refract Surg. 2015 Jun;41(6):1176-81. doi: 10.1016/j.jcrs.2014.09.040. Epub 2015 Jun 19.
To evaluate the relationship between baseline corneal hysteresis (CH) and the change in intraocular pressure (IOP) before and after cataract extraction in patients without glaucoma.
Private practice, New York City, New York, USA.
Retrospective cohort study.
Charts of consecutive patients who had phacoemulsification cataract extraction with posterior chamber intraocular lens implantation were analyzed. All included patients had preoperative and postoperative measurements with the Ocular Response Analyzer 2 to 4 months and 10 to 12 months postoperatively. Data collected included age, baseline CH, baseline central corneal thickness (CCT), and IOP.
Thirty nine (65 eyes) of the 230 patients met the inclusion criteria. The mean patient age was 70.8 years ± 8.6 (SD). The mean preoperative, 2- to 4-month and 10- to 12- month postoperative IOP values were 14.8 ± 3.5 mm Hg, 11.9 ± 3.4 mm Hg, and 12.6 ± 3.1 mm Hg, respectively (P < .05 for comparisons with preoperative IOP). The baseline CH was not predictive of the IOP reduction at 2 to 4 months (β = -0.3; 95% confidence interval [CI], -0.7 to 0.01; P = .06). However, the baseline CH (but not the baseline CCT) was statistically associated with the magnitude of IOP reduction at 10 to 12 months when controlling for patient age (β = -0.5; 95% CI, -0.8 to -0.1; P = .01).
A low baseline CH was associated with a larger magnitude of IOP reduction after cataract extraction.
Dr. Radcliffe is a consultant to Reichert Technologies and Glaukos Corp.; a consultant to and speaker for Allergan, Inc., Alcon Laboratories, Inc., Iridex Corp., Merge Healthcare, Carl Zeiss Meditec AG; and a speaker for Merck Pharmaceuticals. No other author has a financial or proprietary interest in any material or method mentioned.
评估无青光眼患者白内障摘除术前、后的基线角膜滞后(CH)与眼压(IOP)变化之间的关系。
美国纽约市的私人诊所。
回顾性队列研究。
分析连续接受超声乳化白内障摘除联合后房型人工晶状体植入术患者的病历。所有纳入患者在术后2至4个月以及10至12个月使用眼反应分析仪进行术前和术后测量。收集的数据包括年龄、基线CH、基线中央角膜厚度(CCT)和IOP。
230例患者中有39例(65只眼)符合纳入标准。患者平均年龄为70.8岁±8.6(标准差)。术前、术后2至4个月和10至12个月的平均IOP值分别为14.8±3.5 mmHg、11.9±3.4 mmHg和12.6±3.1 mmHg(与术前IOP比较,P <.05)。基线CH不能预测术后2至4个月的IOP降低情况(β = -0.3;95%置信区间[CI],-0.7至0.01;P =.06)。然而,在控制患者年龄后,基线CH(而非基线CCT)与术后10至12个月IOP降低的幅度具有统计学相关性(β = -0.5;95%CI,-0.8至-0.1;P =.01)。
白内障摘除术后,低基线CH与更大幅度的IOP降低相关。
拉德克利夫医生是Reichert Technologies和Glaukos Corp.的顾问;是Allergan, Inc., Alcon Laboratories, Inc., Iridex Corp., Merge Healthcare, Carl Zeiss Meditec AG的顾问及演讲者;是Merck Pharmaceuticals的演讲者。其他作者对文中提及的任何材料或方法均无财务或专利权益。