Mikkelsen E O, Helmig O, Jakobsen P, Sørensen O S
Ugeskr Laeger. 1989 Jan 2;151(1):28-9.
A double-blind, cross-over investigation undertaken of the bioaccessibility of diazepam in 12 healthy volunteers revealed that there is no significant difference as regards the bio-accessibility of diazepam administered as Valaxon or as Valium tablets. It is concluded that pharmokinetic studies such as this can provide important clinical information and are easy to carry out in a hospital department.
一项针对12名健康志愿者进行的关于地西泮生物可及性的双盲交叉研究表明,以Valaxon或安定片形式给药的地西泮在生物可及性方面没有显著差异。得出的结论是,这样的药代动力学研究可以提供重要的临床信息,并且在医院科室中易于开展。