生物相容性壳聚糖/聚乙烯醇共混物选定性能的评估
Evaluation of selected properties of biocompatible chitosan/poly(vinyl alcohol) blends.
作者信息
Islam Atif, Yasin Tariq, Gull Nafisa, Khan Shahzad Maqsood, Munawar Muhammad Azeem, Shafiq Muhammad, Sabir Aneela, Jamil Tahir
机构信息
Department of Polymer Engineering and Technology, University of the Punjab, Lahore, Pakistan; Department of Metallurgy and Materials Engineering, PIEAS, Nilore, Islamabad, Pakistan.
Department of Metallurgy and Materials Engineering, PIEAS, Nilore, Islamabad, Pakistan.
出版信息
Int J Biol Macromol. 2016 Jan;82:551-6. doi: 10.1016/j.ijbiomac.2015.09.073. Epub 2015 Oct 3.
Selected properties of chitosan (CS) and poly(vinyl alcohol) (PVA) blends crosslinked by tetraethoxysilane (TEOS) were studied. XRD analysis showed characteristics peak at 22.5° attributed to the crystalline structure of CS and PVA. DSC thermograms unveiled the quantitative determination of free, intermediate and bound water in the blends. Tensile strength and fracture strain of blends were observed due to the combined effect of physically and chemically crosslinked network structures. The decrease in water contact angle indorsed the hydrophilic performance while the storage modulus G' and loss modulus G″ was decreased as the temperature was increased exhibited the viscoelastic property of the blends. The fabricated blends can be employed for drug delivery systems, tissue engineering and other biomedical applications.
研究了通过四乙氧基硅烷（TEOS）交联的壳聚糖（CS）和聚乙烯醇（PVA）共混物的选定性能。X射线衍射（XRD）分析显示在22.5°处有特征峰，归因于CS和PVA的晶体结构。差示扫描量热法（DSC）热重曲线揭示了共混物中游离水、中间水和结合水的定量测定。由于物理和化学交联网络结构的综合作用，观察到了共混物的拉伸强度和断裂应变。水接触角的减小证实了亲水性，而随着温度升高储能模量G'和损耗模量G''降低，表现出共混物的粘弹性。所制备的共混物可用于药物递送系统、组织工程和其他生物医学应用。
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