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阿联酋阿布扎比酋长国宫颈癌筛查女性的年龄特异性细胞学异常

Age Specific Cytological Abnormalities in Women Screened for Cervical Cancer in the Emirate of Abu Dhabi.

作者信息

Al Zaabi Muna, Al Muqbali Shaikha, Al Sayadi Thekra, Al Ameeri Suhaila, Coetsee Karin, Balayah Zuhur, Ortashi Osman

机构信息

Family Medicine, Ambulatory Healthcare Services, Al Ain, United Arab Emirates E-mail :

出版信息

Asian Pac J Cancer Prev. 2015;16(15):6375-9. doi: 10.7314/apjcp.2015.16.15.6375.

Abstract

BACKGROUND

Cervical cancer is the second most common cancer in women worldwide, with about 500,000 new cases and 270,000 deaths each year. Globally, it is estimated that over one million women currently have cervical cancer, most of whom have not been diagnosed, or have no access to treatment that could cure them or prolong their lives. In the United Arab Emirates (UAE) cervical cancer is the third most common cancer in women.

MATERIALS AND METHODS

A population-based cross-sectional retrospective survey of cervical smear abnormalities was conducted in the Emirate of Abu Dhabi, UAE, from January 2013 to December 2013 by collecting consecutive liquid-based cytology samples from the Department of Pathology at the SKMC Hospital in Abu Dhabi city.

RESULTS

The total number of women screened for cervical cancer for the year 2013 at SKMC was 4,593, with 225 (4.89%) abnormal smears. The majority of the abnormal smear results were atypical squamous cells of undetermined significance (ASCUS) 114 (2.48%). This study showed 60% increase in the rate of abnormal cervical smears in the UAE over the last 10 years. In this study the highest incidence of high grade abnormalities were seen in women above the age of 61 years (1.73%), this might be due to the fact that this group of women missed the chance of screening of cervical cancer earlier in their lives or could be explained by the well-known second peak of HPV infection seen in many prevalence studies.

CONCLUSIONS

We conclude that the rate of abnormal cervical smear in the screened Abu Dhabi women is not different from the rate in developed countries. A notable increase in both low and high grade abnormalities has occurred within the last decade.

摘要

背景

宫颈癌是全球女性中第二常见的癌症,每年约有50万新发病例和27万例死亡。据估计,全球目前有超过100万女性患有宫颈癌,其中大多数尚未被诊断出来,或者无法获得能够治愈她们或延长其生命的治疗。在阿拉伯联合酋长国(阿联酋),宫颈癌是女性中第三常见的癌症。

材料与方法

2013年1月至2013年12月,在阿联酋阿布扎比酋长国开展了一项基于人群的宫颈涂片异常横断面回顾性调查,通过从阿布扎比市SKMC医院病理科收集连续的液基细胞学样本进行。

结果

2013年在SKMC接受宫颈癌筛查的女性总数为4593人,其中225人(4.89%)涂片异常。大多数异常涂片结果为意义不明确的非典型鳞状细胞(ASCUS),共114例(2.48%)。本研究表明,过去10年阿联酋宫颈涂片异常率上升了60%。在本研究中,61岁以上女性的高级别异常发生率最高(1.73%),这可能是因为这组女性在早年错过了宫颈癌筛查的机会,或者可以用许多患病率研究中发现的人乳头瘤病毒(HPV)感染的第二个高峰来解释。

结论

我们得出结论,接受筛查的阿布扎比女性宫颈涂片异常率与发达国家无异。在过去十年中,低级别和高级别异常均显著增加。

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