Agrawal Tanu, Shrinivas Teerthanath, Permi Harish S, Kukreja Prachi, Shetty Jayaprakash
Post Graduate, Department of Pathology, K S Hegde Medical Academy , Mangalore, India .
Professor, Department of Pathology, K S Hegde Medical Academy , Mangalore, India .
J Clin Diagn Res. 2015 Aug;9(8):ED11-3. doi: 10.7860/JCDR/2015/12758.6325. Epub 2015 Aug 1.
Metaplastic carcinoma of breast (MBC) is a rare and aggressive type of invasive breast cancer. As it encompasses a variety of distinct histopathologic designations, diagnostic challenges abound. We present a case report of metaplastic carcinoma with extensive chondroid differentiation. This case merits presentation because of its rarity and difficulty to diagnose, especially if the tumour is composed mainly of sarcomatous elements. Standard chemotherapy regimes are ineffective against MBC. The prognosis of MBC is poor in comparison to classical invasive breast cancer. Data focusing on MBC is limited due to its rare incidence.
乳腺化生性癌(MBC)是一种罕见且侵袭性强的浸润性乳腺癌。由于它包含多种不同的组织病理学类型,诊断面临诸多挑战。我们报告一例具有广泛软骨样分化的化生性癌病例。该病例因其罕见性及诊断困难而值得报道,尤其是当肿瘤主要由肉瘤样成分构成时。标准化疗方案对MBC无效。与经典浸润性乳腺癌相比,MBC的预后较差。由于其发病率低,关于MBC的数据有限。