Nandanwar Avinash S, Patil Yogita, Wagaskar Vinayak G, Baheti Vidyasagar H, Tanwar Harshwardhan V, Patwardhan Sujata K
Resident, Department of Anaesthesia, King's Edward Memorial Hospital and S.G.S. Medical College , Mumbai, India .
Associate Professor, Department of Anaesthesia, King's Edward Memorial Hospital and S.G.S. Medical College , Mumbai, India .
J Clin Diagn Res. 2015 Aug;9(8):UC01-4. doi: 10.7860/JCDR/2015/14091.6301. Epub 2015 Aug 1.
Percutaneous nephrolithotomy (PCNL) is done under general anaesthesia in most of the centres. Associated complications and cost are higher for general anaesthesia than for regional anaesthesia. Present study is designed to compare the efficacy of epidural block versus spinal anaesthesia with regards to intraoperative mean arterial pressure, heart rate, postoperative pain intensity, analgesic requirement, Postoperative complications and patient satisfaction in patients undergoing PCNL.
After taking Ethical Committee clearance, patients were randomly allocated into 2 groups using table of randomization (n= 40 each) Group E- Epidural block, Group S- Spinal block. Various parameters like intraoperative mean arterial pressure, heart rate, postoperative pain intensity, analgesic requirement, postoperative complications and patient satisfaction were studied in these groups.
Quantitative data was analysed using unpaired t-test and qualitative data was analysed using chi-square test.
Twenty four times in Epidural as compared to fifteen times in spinal anaesthesia two or more attempts required. Mean time (min) required to achieve the block of anaesthesia in group E and group S was 15.45±2.8 and 8.52±2.62 min respectively. Mean arterial pressure (MAP) at 5 min, 10 min and 15 min were significantly lower in spinal group as compared to epidural group. After 30 minutes, differences were not significant but still MAP was lower in spinal group. After 30 minutes difference in heart rate between two groups was statistically significant and higher rate recorded in spinal group till the end of 3 hours. Postoperative VAS score was significantly higher in spinal group and 4 hours onwards difference was highly significant. Postoperative Nausea Vomiting (PONV) Score was significantly higher in spinal group as compared to epidural group.
For PCNL, segmental epidural block is better than spinal anaesthesia in terms of haemodynamic stability, postoperative analgesia, patient satisfaction and reduced incidence of PONV. Epidural anaesthesia is difficult to execute and takes longer time to act as compared to spinal block which limits its use.
在大多数中心,经皮肾镜取石术(PCNL)是在全身麻醉下进行的。全身麻醉相关的并发症和费用高于区域麻醉。本研究旨在比较硬膜外阻滞与脊髓麻醉在PCNL患者术中平均动脉压、心率、术后疼痛强度、镇痛需求、术后并发症及患者满意度方面的效果。
获得伦理委员会批准后,使用随机数字表将患者随机分为两组(每组n = 40):E组 - 硬膜外阻滞,S组 - 脊髓阻滞。对这些组中的各种参数进行研究,如术中平均动脉压、心率、术后疼痛强度、镇痛需求、术后并发症及患者满意度。
定量数据采用成组t检验分析,定性数据采用卡方检验分析。
硬膜外麻醉需要两次或更多次尝试的情况有24次,而脊髓麻醉为15次。E组和S组达到麻醉阻滞所需的平均时间(分钟)分别为15.45±2.8和8.52±2.62分钟。与硬膜外组相比,脊髓组在5分钟、10分钟和15分钟时的平均动脉压(MAP)显著较低。30分钟后,差异不显著,但脊髓组的MAP仍然较低。两组心率在30分钟后的差异具有统计学意义,直到3小时结束脊髓组的心率一直较高。脊髓组术后视觉模拟评分(VAS)显著更高,4小时后差异极为显著。与硬膜外组相比,脊髓组术后恶心呕吐(PONV)评分显著更高。
对于PCNL,在血流动力学稳定性、术后镇痛、患者满意度及降低PONV发生率方面,节段性硬膜外阻滞优于脊髓麻醉。与脊髓阻滞相比,硬膜外麻醉操作困难且起效时间更长,这限制了其应用。